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NARFL Antibody

  • 中文名称：
    NARFL兔多克隆抗体
  • 货号：
    CSB-PA015455GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9H6Q4
  • 基因名：
    NARFL
  • 别名：
    CIAO3 antibody; NARFL antibody; PRNCytosolic iron-sulfur assembly component 3 antibody; Cytosolic Fe-S cluster assembly factor NARFL antibody; Iron-only hydrogenase-like protein 1 antibody; IOP1 antibody; Nuclear prelamin A recognition factor-like protein antibody; Protein related to Narf antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human NARFL-Specific
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.
  • 基因功能参考文献：
    1. we concluded that the Ser161Ile mutant induced NARFL deficiency and eventually diffuse PAVMs probably through VEGF pathway. In a word, we detected a functional mutation in NARFL, which might be the pathogenic gene in this pedigree. PMID: 27835862
    2. IOP1 is involved in mammalian cytosolic Fe-S protein maturation. PMID: 18270200
    3. human IscA1 plays an important role in both mitochondrial and cytosolic iron-sulfur cluster biogenesis, and a notable component of the latter is the interaction between IscA1 and IOP1. PMID: 19864422
  • 蛋白家族：
    NARF family
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 14179

    OMIM: 611118

    KEGG: hsa:64428

    STRING: 9606.ENSP00000251588

    UniGene: Hs.513247