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NUP133 Antibody

  • 中文名称：
    NUP133兔多克隆抗体
  • 货号：
    CSB-PA016189GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q8WUM0
  • 基因名：
    NUP133
  • 别名：
    133 kDa nucleoporin antibody; FLJ10814 antibody; hNUP 133 antibody; hNUP133 antibody; MGC21133 antibody; NU133_HUMAN antibody; Nuclear pore complex protein Nup133 antibody; Nucleoporin 133kDa antibody; Nucleoporin NUP133 antibody; NUP 133 antibody; NUP133 antibody; OTTHUMP00000061095 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human NUP133
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in poly(A)+ RNA transport. Involved in nephrogenesis.
  • 基因功能参考文献：
    1. human Nup133 contains two domains: a COOH-terminal domain responsible for its interaction with its subcomplex through Nup107; and an NH2-terminal domain whose crystal structure reveals a seven-bladed beta-propeller. PMID: 15557116
    2. When complexed with NUP107, this complex will give the first insights into the protein-protein interactions within a core module of the nuclear pore complex. PMID: 17768364
    3. The significant topological differences between Nup107 and Nup133 suggest that helical nucleoporin domains of the nuclear pore complex scaffold fall in different classes and fulfill largely nonredundant functions. PMID: 18570875
    4. Data present crystal structures of yNup170(979-1502) and hNup107(658-925) x hNup133(517-1156), and conservation of domain arrangement and of tertiary structure suggests that Nup157/170 and Nup133 derived from a common ancestor. PMID: 19674973
  • 亚细胞定位：
    Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore.
  • 蛋白家族：
    Nucleoporin Nup133 family
  • 组织特异性：
    Widely expressed in fetal and adult tissues. Expressed in the brain and kidney.
  • 数据库链接：

    HGNC: 18016

    OMIM: 607613

    KEGG: hsa:55746

    STRING: 9606.ENSP00000261396

    UniGene: Hs.12457