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PGLYRP2 Antibody

  • 货号：
    CSB-PA846684LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA846684LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA846684LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PGLYRP2 Polyclonal antibody
  • Uniprot No.：
    Q96PD5
  • 基因名：
    PGLYRP2
  • 别名：
    PGLYRP2 antibody; PGLYRPL antibody; PGRPL antibody; UNQ3103/PRO10102 antibody; N-acetylmuramoyl-L-alanine amidase antibody; EC 3.5.1.28 antibody; Peptidoglycan recognition protein 2 antibody; Peptidoglycan recognition protein long antibody; PGRP-L antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human N-acetylmuramoyl-L-alanine amidase protein (22-576AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PGLYRP2 Antibody (CSB-PA846684LA01HU)，的标记方式是Non-conjugated。对于PGLYRP2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA846684LB01HU PGLYRP2 Antibody, HRP conjugated ELISA
    FITC CSB-PA846684LC01HU PGLYRP2 Antibody, FITC conjugated
    Biotin CSB-PA846684LD01HU PGLYRP2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity.
  • 基因功能参考文献：
    1. This study demonistrated that PGLYRP2 single-nucleotide polymorphisms is risk of Parkinson's disease. PMID: 24838182
    2. Various types of human blood cells were tested for expression of the Tag7/PGRP-SA and TagL/PGRP-L proteins, which belong to the family of proteins possessing the lysozyme-like peptidoglycan recognition protein (PGRP) domain PMID: 12669421
    3. Serum N-acetylmuramoyl-l-alanine amidaseand liver PGLYRP2 are the same protein encoded by the pglyrp2 gene. PMID: 16054449
    4. PGLYRP2 may function in the skin and the eyes as an inducible scavenger of proinflammatory peptidoglycan. PMID: 16239516
    5. pglyrp2 expression in skin and liver is important for systemic and local innate immune responses to bacterial infections PMID: 16714290

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  • 亚细胞定位：
    Secreted. Membrane.
  • 蛋白家族：
    N-acetylmuramoyl-L-alanine amidase 2 family
  • 组织特异性：
    Strongly expressed in liver and fetal liver, and secreted into serum. Expressed to a much lesser extent in transverse colon, lymph nodes, heart, thymus, pancreas, descending colon, stomach and testis. Isoform 2 is not detected in the liver or serum.
  • 数据库链接：

    HGNC: 30013

    OMIM: 608199

    KEGG: hsa:114770

    STRING: 9606.ENSP00000345968

    UniGene: Hs.282244