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PIGK Antibody

  • 货号：
    CSB-PA842143LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: HepG2 whole cell lysate, A549 whole cell lysate
      All lanes: PIGK antibody at 2.5µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 46, 37 kDa
      Observed band size: 46 kDa
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA842143LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PIGK Polyclonal antibody
  • Uniprot No.：
    Q92643
  • 基因名：
    PIGK
  • 别名：
    PIGK antibody; GPI8 antibody; GPI-anchor transamidase antibody; GPI transamidase antibody; EC 3.-.-.- antibody; GPI8 homolog antibody; hGPI8 antibody; Phosphatidylinositol-glycan biosynthesis class K protein antibody; PIG-K antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human GPI-anchor transamidase protein (91-293AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PIGK Antibody (CSB-PA842143LA01HU)，的标记方式是Non-conjugated。对于PIGK Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA842143LB01HU PIGK Antibody, HRP conjugated ELISA
    FITC CSB-PA842143LC01HU PIGK Antibody, FITC conjugated
    Biotin CSB-PA842143LD01HU PIGK Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.
  • 基因功能参考文献：
    1. Report firstly demonstrated that inadequate protein-glycosylphosphatidylinositol anchoring caused by suppression of PIGK might affect the expression or function of some glycosylphosphatidylinositol-anchored proteins associated with tyrosinase activity. PMID: 27919619
    2. Our results demonstrate, for the first time, a link between the SNP 1048575 and low PIGK expression in CRC/HCC patients and also suggest a possible association between altered PIGK expression and disease susceptibility. PMID: 22824918
    3. GPI8 and PIG-T form a functionally important intermolecular disulfide bridge PMID: 12582175
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Peptidase C13 family
  • 数据库链接：

    HGNC: 8965

    OMIM: 605087

    KEGG: hsa:10026

    STRING: 9606.ENSP00000359848

    UniGene: Hs.178305