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PIGK Antibody

  • 货号：
    CSB-PA017974GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q92643
  • 基因名：
    PIGK
  • 别名：
    PIGK antibody; GPI8 antibody; GPI-anchor transamidase antibody; GPI transamidase antibody; EC 3.-.-.- antibody; GPI8 homolog antibody; hGPI8 antibody; Phosphatidylinositol-glycan biosynthesis class K protein antibody; PIG-K antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human PIGK
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.
  • 基因功能参考文献：
    1. Report firstly demonstrated that inadequate protein-glycosylphosphatidylinositol anchoring caused by suppression of PIGK might affect the expression or function of some glycosylphosphatidylinositol-anchored proteins associated with tyrosinase activity. PMID: 27919619
    2. Our results demonstrate, for the first time, a link between the SNP 1048575 and low PIGK expression in CRC/HCC patients and also suggest a possible association between altered PIGK expression and disease susceptibility. PMID: 22824918
    3. GPI8 and PIG-T form a functionally important intermolecular disulfide bridge PMID: 12582175
  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Peptidase C13 family
  • 数据库链接：

    HGNC: 8965

    OMIM: 605087

    KEGG: hsa:10026

    STRING: 9606.ENSP00000359848

    UniGene: Hs.178305