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PLEKHB2 Antibody

  • 货号：
    CSB-PA846599LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA846599LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) PLEKHB2 Polyclonal antibody
  • Uniprot No.：
    Q96CS7
  • 基因名：
    PLEKHB2
  • 别名：
    Evectin 2 antibody; Evectin-2 antibody; Evectin2 antibody; EVT2 antibody; FLJ20783 antibody; FLJ23679 antibody; FLJ30436 antibody; PH domain containing family B member 2 antibody; PH domain-containing family B member 2 antibody; PKHB2_HUMAN antibody; Pleckstrin homology domain containing family B member 2 antibody; Pleckstrin homology domain containing, family B (evectins) member 2 antibody; Pleckstrin homology domain-containing family B member 2 antibody; Plekhb2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Pleckstrin homology domain-containing family B member 2 protein (1-222AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，PLEKHB2 Antibody (CSB-PA846599LA01HU)，的标记方式是Non-conjugated。对于PLEKHB2 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA846599LB01HU PLEKHB2 Antibody, HRP conjugated ELISA
    FITC CSB-PA846599LC01HU PLEKHB2 Antibody, FITC conjugated
    Biotin CSB-PA846599LD01HU PLEKHB2 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in retrograde transport of recycling endosomes.
  • 基因功能参考文献：
    1. Knockdown of evectin-2 (a recycling endosome-resident protein) suppresses nuclear localization of YAP and YAP-dependent transcription. Evectin-2 knockdown reduces the ubiquitination and increased the level of Lats1. PMID: 29093443
    2. The crystal structure at 1.75 A resolution of an apo form of human evectin-2 pleckstrin homology domain, in which the ligand-binding site is free from crystal packing and is thus appropriate for comparison with the structure of the complex, is reported. PMID: 22281740
    3. Data show that depletion of evt-2 or masking of intracellular PS suppressed membrane traffic from REs to the Golgi. PMID: 21911378
  • 亚细胞定位：
    Recycling endosome membrane; Peripheral membrane protein. Note=Specifically detected in tubulovesicular structures, and colocalizes with TFNR.
  • 数据库链接：

    HGNC: 19236

    KEGG: hsa:55041

    STRING: 9606.ENSP00000385892

    UniGene: Hs.469944