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PSMD7 Antibody

  • 货号：
    CSB-PA697643
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA697643(PSMD7 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA697643(PSMD7 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    P51665
  • 基因名：
    PSMD7
  • 别名：
    26S proteasome non ATPase regulatory subunit 7 antibody; 26S proteasome non-ATPase regulatory subunit 7 antibody; 26S proteasome regulatory subunit RPN8 antibody; 26S proteasome regulatory subunit S12 antibody; integration site gene; mouse; homolog of antibody; Moloney leukemia virus 34 proviral antibody; Moloney leukemia virus 34 proviral integration antibody; MOV34 antibody; Mov34 homolog antibody; Mov34 protein homolog antibody; MOV34L antibody; P40 antibody; Proteasome (prosome; macropain) 26S subunit; non ATPase 7 antibody; Proteasome (prosome; macropain) 26S subunit; non ATPase; 7 (Mov34 homolog) antibody; Proteasome 26S S12 antibody; Proteasome 26S subunit; no-ATPase; 7 antibody; Proteasome subunit p40 antibody; PSD7_HUMAN antibody; PSMD 7 antibody; PSMD7 antibody; Rpn8 antibody; S12 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human PSMD7
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
  • 基因功能参考文献：
    1. SNP rs17336700 of a non-MHC ubiquitin-proteasome subunit PSMD7 is significantly associated with ankylosing spondylitis in Chinese population and the mRNA level of the PSMD7 gene in liver tissue increased when the rs17336700 C allele was present. PMID: 20643764
    2. hVIP is a member of the complex array of nucleocytoplasmic shuttling proteins that are regulated by HIV infection and glucocorticoids PMID: 12237292
    3. data suggest a differential nuclear function of modified and unmodified S12 in cancer PMID: 15221960
    4. MPN domain of Mov34 is highly resistant to proteolysis PMID: 16842755
    5. although the MPN domain of Mov34 shows a typical metalloprotease fold, it is unable to coordinate a metal ion. PMID: 17559875

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  • 蛋白家族：
    Peptidase M67A family
  • 数据库链接：

    HGNC: 9565

    OMIM: 157970

    KEGG: hsa:5713

    STRING: 9606.ENSP00000219313

    UniGene: Hs.440604