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  4. Recombinant Human 26S proteasome non-ATPase regulatory subunit 7 (PSMD7)

Recombinant Human 26S proteasome non-ATPase regulatory subunit 7 (PSMD7)

  • 中文名称：
    人PSMD7重组蛋白
  • 货号：
    CSB-YP018912HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人PSMD7重组蛋白
  • 货号：
    CSB-EP018912HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人PSMD7重组蛋白
  • 货号：
    CSB-EP018912HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人PSMD7重组蛋白
  • 货号：
    CSB-BP018912HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人PSMD7重组蛋白
  • 货号：
    CSB-MP018912HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PSMD7
  • Uniprot No.：
  • 别名：
    26S proteasome non ATPase regulatory subunit 7; 26S proteasome non-ATPase regulatory subunit 7; 26S proteasome regulatory subunit RPN8; 26S proteasome regulatory subunit S12; integration site gene; mouse; homolog of; Moloney leukemia virus 34 proviral; Moloney leukemia virus 34 proviral integration; MOV34; Mov34 homolog; Mov34 protein homolog; MOV34L; P40; Proteasome (prosome; macropain) 26S subunit; non ATPase 7; Proteasome (prosome; macropain) 26S subunit; non ATPase; 7 (Mov34 homolog); Proteasome 26S S12; Proteasome 26S subunit; no-ATPase; 7; Proteasome subunit p40; PSD7_HUMAN; PSMD 7; PSMD7; Rpn8; S12
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-324
  • 氨基酸序列
    MPELAVQKVV VHPLVLLSVV DHFNRIGKVG NQKRVVGVLL GSWQKKVLDV SNSFAVPFDE DDKDDSVWFL DHDYLENMYG MFKKVNARER IVGWYHTGPK LHKNDIAINE LMKRYCPNSV LVIIDVKPKD LGLPTEAYIS VEEVHDDGTP TSKTFEHVTS EIGAEEAEEV GVEHLLRDIK DTTVGTLSQR ITNQVHGLKG LNSKLLDIRS YLEKVATGKL PINHQIIYQL QDVFNLLPDV SLQEFVKAFY LKTNDQMVVV YLASLIRSVV ALHNLINNKI ANRDAEKKEG QEKEESKKDR KEDKEKDKDK EKSDVKKEEK KEKK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
  • 基因功能参考文献：
    1. SNP rs17336700 of a non-MHC ubiquitin-proteasome subunit PSMD7 is significantly associated with ankylosing spondylitis in Chinese population and the mRNA level of the PSMD7 gene in liver tissue increased when the rs17336700 C allele was present. PMID: 20643764
    2. hVIP is a member of the complex array of nucleocytoplasmic shuttling proteins that are regulated by HIV infection and glucocorticoids PMID: 12237292
    3. data suggest a differential nuclear function of modified and unmodified S12 in cancer PMID: 15221960
    4. MPN domain of Mov34 is highly resistant to proteolysis PMID: 16842755
    5. although the MPN domain of Mov34 shows a typical metalloprotease fold, it is unable to coordinate a metal ion. PMID: 17559875

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  • 蛋白家族：
    Peptidase M67A family
  • 数据库链接：

    HGNC: 9565

    OMIM: 157970

    KEGG: hsa:5713

    STRING: 9606.ENSP00000219313

    UniGene: Hs.440604