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Plet1 Antibody

  • 货号：
    CSB-PA851843HA01MO
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: Plet1 antibody at 5µg/ml
      Lane 1: L929 whole cell lysate
      Lane 2: U251 whole cell lysate
      Lane 3: Mouse muscle tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 26, 21 kDa
      Observed band size: 26 kDa
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA851843HA01MO at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA851843HA01MO at dilution of 1:100
  • 其他：

产品详情

  • 产品描述：

    To generate the Plet1 polyclonal antibody, the recombinant mouse Plet1 protein (28-218aa) was administered to a rabbit to induce an immune response. The rabbit blood was collected and purified using protein G affinity chromatography, getting the Plet1 polyclonal antibody. The purity of the Plet1 antibody obtained through this process is over 95%, which ensures the reliability and accuracy of the results.

    This high-purity Plet1 antibody has demonstrated reactivity with both human and mouse samples and has been thoroughly validated for use in various applications, including ELISA, WB, and IHC. These applications enable the detection of the presence and quantity of Plet1 protein, the visualization of its distribution and localization, as well as its identification.

  • 产品名称：
    Rabbit anti-Mus musculus (Mouse) Plet1 Polyclonal antibody
  • Uniprot No.：
    Q8VEN2
  • 基因名：
  • 别名：
    Plet1 antibody; Placenta-expressed transcript 1 protein antibody; Antigen mAgK114 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Mouse, Human
  • 免疫原：
    Recombinant Mouse Placenta-expressed transcript 1 protein (28-218AA)
  • 免疫原种属：
    Mus musculus (Mouse)
  • 标记方式：
    Non-conjugated

    本页面中的产品，Plet1 Antibody (CSB-PA851843HA01MO)，的标记方式是Non-conjugated。对于Plet1 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA851843HB01MO Plet1 Antibody, HRP conjugated ELISA
    FITC CSB-PA851843HC01MO Plet1 Antibody, FITC conjugated
    Biotin CSB-PA851843HD01MO Plet1 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.
  • 基因功能参考文献：
    1. The endogenous dynamics of Plet1 expression establish important patterning cues within the trophoblast compartment by promoting differentiation towards the syncytiotrophoblast or giant cell pathway in Plet1-low and Plet1-high cells, respectively. PMID: 27121762
    2. these results show that IL-17A-induced PLET1 expression contributes to tissue repair and colon tumorigenesis PMID: 29070673
    3. The restricted localization in both differentiated outer root sheath and companion layer cells contacting the hair fiber and epidermal wounds suggests a role for the Plet-1 protein in regulating the interaction of keratinocytes with inert tissues. PMID: 20130590
    4. Plet-1 will thus provide an invaluable tool for genetic analysis of the lineage relationships and molecular mechanisms operating in the development, homeostasis, and injury in several organ/tissue systems PMID: 18195351
  • 亚细胞定位：
    Apical cell membrane; Lipid-anchor, GPI-anchor. Note=Localized at the apical membrane of the most differentiated keratinocytes of the outer root sheath (ORS), clustered mainly in planar regions of the plasma membrane at the base of microvilli.
  • 组织特异性：
    Present in hair follicle cells and sebaceous gland of skin, ciliated epithelial cells of trachea and bronchial tube, striated portion of submandibular gland, distal convoluted tubule cells of kidney, ciliated epithelial cells of oviduct, medulla of adrena
  • 数据库链接：

    KEGG: mmu:76509

    STRING: 10090.ENSMUSP00000110118

    UniGene: Mm.29959