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  4. RFC4 Antibody

RFC4 Antibody

  • 货号：
    CSB-PA019591GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P35249
  • 基因名：
    RFC4
  • 别名：
    A1 37 antibody; A1 37 kDa subunit antibody; Activator 1 37 antibody; Activator 1 37 kDa subunit antibody; Activator 1 subunit 4 antibody; Replication factor C 37 antibody; Replication factor C 37 kDa subunit antibody; Replication factor C subunit 4 antibody; Replication factor C4 antibody; RF-C 37 kDa subunit antibody; RFC 37 antibody; RFC37 antibody; RFC4 replication factor C (activator 1)4 37kDa antibody; RfC4 antibody; RFC4_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human RFC4
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.
  • 基因功能参考文献：
    1. Expression level of RFC4 was up regulated in cervical squamous cell carcinoma. PMID: 28341182
    2. RFC4 is frequently overexpressed in CRC, and is associated with tumor progression and worse survival outcome. This might be attributed to the regulation of CRC cell proliferation and cell cycle arrest by RFC4 PMID: 25407051
    3. The knockdown of endogenous replication factor C4 decreases the growth and enhances the chemosensitivity of hepatocellular carcinoma cells. PMID: 18492021
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Activator 1 small subunits family
  • 数据库链接：

    HGNC: 9972

    OMIM: 102577

    KEGG: hsa:5984

    STRING: 9606.ENSP00000296273

    UniGene: Hs.732098