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RFC4 Antibody

  • 货号：
    CSB-PA019591LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: Raji whole cell lysate, Hela whole cell lysate, Mouse kidney tissue
      All lanes: RFC4 antibody at 2.7μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 40, 34 kDa
      Observed band size: 40 kDa
    • Immunofluorescent analysis of HepG2 cells using CSB-PA019591LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) RFC4 Polyclonal antibody
  • Uniprot No.：
    P35249
  • 基因名：
    RFC4
  • 别名：
    A1 37 antibody; A1 37 kDa subunit antibody; Activator 1 37 antibody; Activator 1 37 kDa subunit antibody; Activator 1 subunit 4 antibody; Replication factor C 37 antibody; Replication factor C 37 kDa subunit antibody; Replication factor C subunit 4 antibody; Replication factor C4 antibody; RF-C 37 kDa subunit antibody; RFC 37 antibody; RFC37 antibody; RFC4 replication factor C (activator 1)4 37kDa antibody; RfC4 antibody; RFC4_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Replication factor C subunit 4 protein (9-142AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，RFC4 Antibody (CSB-PA019591LA01HU)，的标记方式是Non-conjugated。对于RFC4 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA019591LB01HU RFC4 Antibody, HRP conjugated ELISA
    FITC CSB-PA019591LC01HU RFC4 Antibody, FITC conjugated
    Biotin CSB-PA019591LD01HU RFC4 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IF
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IF 1:50-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit may be involved in the elongation of the multiprimed DNA template.
  • 基因功能参考文献：
    1. Expression level of RFC4 was up regulated in cervical squamous cell carcinoma. PMID: 28341182
    2. RFC4 is frequently overexpressed in CRC, and is associated with tumor progression and worse survival outcome. This might be attributed to the regulation of CRC cell proliferation and cell cycle arrest by RFC4 PMID: 25407051
    3. The knockdown of endogenous replication factor C4 decreases the growth and enhances the chemosensitivity of hepatocellular carcinoma cells. PMID: 18492021
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Activator 1 small subunits family
  • 数据库链接：

    HGNC: 9972

    OMIM: 102577

    KEGG: hsa:5984

    STRING: 9606.ENSP00000296273

    UniGene: Hs.732098