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  4. S Antibody
  • 货号：
    CSB-PA336163EA01HIY
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 其他：

产品详情

  • 产品描述：

    Rabbits were immunized with recombinant human coronavirus OC43 spike glycoprotein protein (15-344aa) to generate the CSB-PA321224LA01BUA polyclonal antibody against the spike protein. The spike protein of human coronavirus OC43 is an essential component of the virus and plays a crucial role in its pathogenesis, making it a potential target for the development of vaccines and therapeutics.

    Following protein G purification, the rabbit anti-human coronavirus OC43 S polyclonal antibody achieved a purity level of 95%. This non-conjugated IgG specifically binds to the spike protein of human coronavirus OC43 and can detect endogenous levels of the protein, as demonstrated by ELISA.

  • 产品名称：
    Rabbit anti-Human coronavirus OC43 S Polyclonal antibody
  • Uniprot No.：
    P36334
  • 基因名：
  • 别名：
    S antibody; 3Spike glycoprotein antibody; S glycoprotein antibody; E2 antibody; Peplomer protein) [Cleaved into: Spike protein S1; Spike protein S2; Spike protein S2'] antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human coronavirus OC43
  • 免疫原：
    Recombinant Human coronavirus OC43 Spike glycoprotein protein (15-344AA)
  • 免疫原种属：
    Human coronavirus OC43
  • 标记方式：
    Non-conjugated

    本页面中的产品，S Antibody (CSB-PA336163EA01HIY)，的标记方式是Non-conjugated。对于S Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA336163EB01HIY S Antibody, HRP conjugated ELISA
    FITC CSB-PA336163EC01HIY S Antibody, FITC conjugated
    Biotin CSB-PA336163ED01HIY S Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    S1 attaches the virion to the cell membrane by interacting with sialic acid-containing cell receptors, initiating the infection.; attaches the virion to the cell membrane by interacting with host receptor, initiating the infection.; mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.; Acts as a viral fusion peptide which is unmasked following S2 cleavage occurring upon virus endocytosis.
  • 亚细胞定位：
    Virion membrane; Single-pass type I membrane protein. Host endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Host cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Betacoronaviruses spike protein family