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SEPT14 Antibody

  • 货号：
    CSB-PA009478
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of 3T3 cells using Septin 14 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q6ZU15
  • 基因名：
    SEPT14
  • 别名：
    FLJ44060 antibody; SEP14_HUMAN antibody; SEPT 14 antibody; Sept14 antibody; Septin 14 antibody; Septin-14 antibody; Septin14 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human Septin 14.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Filament-forming cytoskeletal GTPase (Probable). Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development. Plays a role in sperm head formation during spermiogenesis, potentially via facilitating localization of ACTN4 to cell filaments.
  • 基因功能参考文献：
    1. The three SEPT14 SNPs defined a protective haplotype which significantly reduced the risk for Parkinson disease was found to be expressed in the brain. PMID: 27115672
    2. SEPT14 maps to 7p11.2 and includes a conserved GTPase domain and a predicted carboxy-terminus coiled-coil domain characteristic of other septins. PMID: 17922164
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Perikaryon. Cytoplasm, perinuclear region. Cytoplasmic vesicle, secretory vesicle, acrosome.
  • 蛋白家族：
    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
  • 组织特异性：
    Testis-specific (at protein level).
  • 数据库链接：

    HGNC: 33280

    OMIM: 612140

    KEGG: hsa:346288

    STRING: 9606.ENSP00000373627

    UniGene: Hs.453629