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  4. Recombinant Human Septin-14 (41531)

Recombinant Human Septin-14 (41531)

  • 货号：
    CSB-YP741068HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP741068HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP741068HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP741068HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP741068HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SEPT14
  • Uniprot No.：
  • 别名：
    FLJ44060; SEP14_HUMAN; SEPT 14; Sept14; Septin 14; Septin-14; Septin14
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-432
  • 氨基酸序列
    MAERTMAMPT QIPADGDTQK ENNIRCLTTI GHFGFECLPN QLVSRSIRQG FTFNILCVGE TGIGKSTLID TLFNTNLKDN KSSHFYSNVG LQIQTYELQE SNVQLKLTVV ETVGYGDQID KEASYQPIVD YIDAQFEAYL QEELKIKRSL FEYHDSRVHV CLYFISPTGH SLKSLDLLTM KNLDSKVNII PLIAKADTIS KNDLQTFKNK IMSELISNGI QIYQLPTDEE TAAQANSSVS GLLPFAVVGS TDEVKVGKRM VRGRHYPWGV LQVENENHCD FVKLRDMLLC TNMENLKEKT HTQHYECYRY QKLQKMGFTD VGPNNQPVSF QEIFEAKRQE FYDQCQREEE ELKQRFMQRV KEKEATFKEA EKELQDKFEH LKMIQQEEIR KLEEEKKQLE GEIIDFYKMK AASEALQTQL STDTKKDKHR KK
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Filament-forming cytoskeletal GTPase (Probable). Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development. Plays a role in sperm head formation during spermiogenesis, potentially via facilitating localization of ACTN4 to cell filaments.
  • 基因功能参考文献：
    1. The three SEPT14 SNPs defined a protective haplotype which significantly reduced the risk for Parkinson disease was found to be expressed in the brain. PMID: 27115672
    2. SEPT14 maps to 7p11.2 and includes a conserved GTPase domain and a predicted carboxy-terminus coiled-coil domain characteristic of other septins. PMID: 17922164
  • 亚细胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton. Cell projection, axon. Cell projection, dendrite. Perikaryon. Cytoplasm, perinuclear region. Cytoplasmic vesicle, secretory vesicle, acrosome.
  • 蛋白家族：
    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
  • 组织特异性：
    Testis-specific (at protein level).
  • 数据库链接：

    HGNC: 33280

    OMIM: 612140

    KEGG: hsa:346288

    STRING: 9606.ENSP00000373627

    UniGene: Hs.453629