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SERPINB8 Antibody

  • 货号：
    CSB-PA961315
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA961315(SERPINB8 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA961315(SERPINB8 Antibody) at dilution 1/400 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 15 seconds
  • 其他：

产品详情

  • Uniprot No.：
    P50452
  • 基因名：
    SERPINB8
  • 别名：
    CAP 2 antibody; CAP-2 antibody; CAP2 antibody; Cytoplasmic antiproteinase 2 antibody; OTTHUMP00000067000 antibody; OTTHUMP00000067001 antibody; Peptidase inhibitor 8 antibody; PI 8 antibody; PI-8 antibody; PI8 antibody; Protease inhibitor 8 (ovalbumin type) antibody; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 8 antibody; Serpin B8 antibody; Serpin peptidase inhibitor clade B (ovalbumin) member 8 antibody; Serpinb8 antibody; SPB8_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Full length fusion protein
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has an important role in epithelial desmosome-mediated cell-cell adhesion.
  • 基因功能参考文献：
    1. report of mutations in SERPINB8 that are associated with exfoliative ichthyosis and provide evidence that SERPINB8 contributes to the mechanical stability of intercellular adhesions in the epidermis PMID: 27476651
    2. PI8 is released by platelets and controls functional responses PMID: 16493485
    3. Data show that SERPINB8 is expressed in normal neuroendocrine cells of several organs as well as in neuroendocrine tumors of the pancreas, where it can be used as an additional diagnostic immunohistochemical marker. PMID: 19188865
  • 相关疾病：
    Peeling skin syndrome 5 (PSS5)
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Serpin family, Ov-serpin subfamily
  • 数据库链接：

    HGNC: 8952

    OMIM: 601697

    KEGG: hsa:5271

    STRING: 9606.ENSP00000331368

    UniGene: Hs.368077