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  4. Recombinant Human Serpin B8 (SERPINB8)

Recombinant Human Serpin B8 (SERPINB8)

  • 中文名称：
    人SERPINB8重组蛋白
  • 货号：
    CSB-YP021076HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SERPINB8重组蛋白
  • 货号：
    CSB-EP021076HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SERPINB8重组蛋白
  • 货号：
    CSB-EP021076HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SERPINB8重组蛋白
  • 货号：
    CSB-BP021076HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SERPINB8重组蛋白
  • 货号：
    CSB-MP021076HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SERPINB8
  • Uniprot No.：
  • 别名：
    CAP 2; CAP-2; CAP2; Cytoplasmic antiproteinase 2; OTTHUMP00000067000; OTTHUMP00000067001; Peptidase inhibitor 8; PI 8; PI-8; PI8; Protease inhibitor 8 (ovalbumin type); Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 8; Serpin B8; Serpin peptidase inhibitor clade B (ovalbumin) member 8; Serpinb8; SPB8_HUMAN
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-374
  • 氨基酸序列
    MDDLCEANGT FAISLFKILG EEDNSRNVFF SPMSISSALA MVFMGAKGST AAQMSQALCL YKDGDIHRGF QSLLSEVNRT GTQYLLRTAN RLFGEKTCDF LPDFKEYCQK FYQAELEELS FAEDTEECRK HINDWVAEKT EGKISEVLDA GTVDPLTKLV LVNAIYFKGK WNEQFDRKYT RGMLFKTNEE KKTVQMMFKE AKFKMGYADE VHTQVLELPY VEEELSMVIL LPDDNTDLAV VEKALTYEKF KAWTNSEKLT KSKVQVFLPR LKLEESYDLE PFLRRLGMID AFDEAKADFS GMSTEKNVPL SKVAHKCFVE VNEEGTEAAA ATAVVRNSRC SRMEPRFCAD HPFLFFIRHH KTNCILFCGR FSSP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Has an important role in epithelial desmosome-mediated cell-cell adhesion.
  • 基因功能参考文献：
    1. report of mutations in SERPINB8 that are associated with exfoliative ichthyosis and provide evidence that SERPINB8 contributes to the mechanical stability of intercellular adhesions in the epidermis PMID: 27476651
    2. PI8 is released by platelets and controls functional responses PMID: 16493485
    3. Data show that SERPINB8 is expressed in normal neuroendocrine cells of several organs as well as in neuroendocrine tumors of the pancreas, where it can be used as an additional diagnostic immunohistochemical marker. PMID: 19188865
  • 相关疾病：
    Peeling skin syndrome 5 (PSS5)
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Serpin family, Ov-serpin subfamily
  • 数据库链接：

    HGNC: 8952

    OMIM: 601697

    KEGG: hsa:5271

    STRING: 9606.ENSP00000331368

    UniGene: Hs.368077