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SLC39A9 Antibody

  • 货号：
    CSB-PA233395
  • 规格：
    ￥2024
  • 图片：
    • Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using at dilution 1/20.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SLC39A9 Polyclonal antibody
  • Uniprot No.：
    Q9NUM3
  • 基因名：
    SLC39A9
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide corresponding to a region derived from internal residues of Human solute carrier family 39, member 9
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:50-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May act as a zinc-influx transporter.
  • 基因功能参考文献：
    1. The study connects structural features of ZIP9 to its functions and indicates a possible relevance of ZIP9 as a pharmacological target PMID: 28943399
    2. ZIP9 role glioblastoma cells migration.ZIP9 expression affects phosphorylation states of p53 and GSK-3beta. PMID: 27654922
    3. The results show ZIP9 is a specific Gi coupled-mAR mediating testosterone-induced MAP kinase and zinc signaling in PC3-ZIP9 cells. PMID: 28219737
    4. ZIP9 expression in glioma tumors was not associated with tumor grade or IDH1 mutation status. PMID: 25921144
    5. ZIP9 mediates testosterone promotion of apoptosis and is widely expressed in human tissues and up-regulated in malignant breast and prostate tissues, suggesting that it is a potential therapeutic target for treating breast and prostate cancers. PMID: 25014355
    6. SLC39A9 functions to regulate zinc homeostasis in the secretory pathway without significantly altering cytosolic zinc homeostasis. PMID: 19420709

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  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ZIP transporter (TC 2.A.5) family
  • 数据库链接：

    HGNC: 20182

    KEGG: hsa:55334

    STRING: 9606.ENSP00000336887

    UniGene: Hs.432690