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  4. Recombinant Human Zinc transporter ZIP9 (SLC39A9), partial

Recombinant Human Zinc transporter ZIP9 (SLC39A9), partial

  • 中文名称：
    人SLC39A9重组蛋白
  • 货号：
    CSB-YP882108HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SLC39A9重组蛋白
  • 货号：
    CSB-EP882108HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SLC39A9重组蛋白
  • 货号：
    CSB-EP882108HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SLC39A9重组蛋白
  • 货号：
    CSB-BP882108HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SLC39A9重组蛋白
  • 货号：
    CSB-MP882108HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SLC39A9
  • Uniprot No.：
  • 别名：
    FLJ11274; MGC74989; PRO1377; S39A9_HUMAN; SLC39A9; Solute carrier family 39 (zinc transporter), member 9; Solute carrier family 39 member 9; UNQ714; Zinc transporter SLC39A9; Zinc transporter ZIP9; ZIP 9; ZIP-9; ZIP9; Zrt- and Irt-like protein 9
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May act as a zinc-influx transporter.
  • 基因功能参考文献：
    1. The study connects structural features of ZIP9 to its functions and indicates a possible relevance of ZIP9 as a pharmacological target PMID: 28943399
    2. ZIP9 role glioblastoma cells migration.ZIP9 expression affects phosphorylation states of p53 and GSK-3beta. PMID: 27654922
    3. The results show ZIP9 is a specific Gi coupled-mAR mediating testosterone-induced MAP kinase and zinc signaling in PC3-ZIP9 cells. PMID: 28219737
    4. ZIP9 expression in glioma tumors was not associated with tumor grade or IDH1 mutation status. PMID: 25921144
    5. ZIP9 mediates testosterone promotion of apoptosis and is widely expressed in human tissues and up-regulated in malignant breast and prostate tissues, suggesting that it is a potential therapeutic target for treating breast and prostate cancers. PMID: 25014355
    6. SLC39A9 functions to regulate zinc homeostasis in the secretory pathway without significantly altering cytosolic zinc homeostasis. PMID: 19420709

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  • 亚细胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ZIP transporter (TC 2.A.5) family
  • 数据库链接：

    HGNC: 20182

    KEGG: hsa:55334

    STRING: 9606.ENSP00000336887

    UniGene: Hs.432690