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SLC6A17 Antibody

  • 中文名称：
    SLC6A17兔多克隆抗体
  • 货号：
    CSB-PA004745
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of rat stomach cells using NTT4 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q9H1V8
  • 基因名：
    SLC6A17
  • 别名：
    SLC6A17 antibody; NTT4 antibody; Sodium-dependent neutral amino acid transporter SLC6A17 antibody; Sodium-dependent neurotransmitter transporter NTT4 antibody; Solute carrier family 6 member 17 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human NTT4.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent.
  • 基因功能参考文献：
    1. Our genetic findings implicate homozygous SLC6A17 mutations in autosomal-recessive intellectual disability. PMID: 25704603
    2. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) PMID: 20379614
    3. The substrate profile of the NTT4/XT1-dependent activity is similar to that of the closely related B(0)AT2/SBAT1 (SLC6A15), including a submillimolar apparent affinity for proline and leucine and a low millimolar apparent affinity for glutamine. PMID: 19147495
  • 相关疾病：
    Mental retardation, autosomal recessive 48 (MRT48)
  • 亚细胞定位：
    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, postsynapse. Cell junction, synapse, presynapse.
  • 蛋白家族：
    Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A17 subfamily
  • 数据库链接：

    HGNC: 31399

    OMIM: 610299

    KEGG: hsa:388662

    STRING: 9606.ENSP00000330199

    UniGene: Hs.128382