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STARD10 Antibody

  • 货号：
    CSB-PA898707
  • 规格：
    ￥2024
  • 图片：
    • Western blot analysis of extracts from COLO205 cells, using STARD10 antibody.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) STARD10 Polyclonal antibody
  • Uniprot No.：
    Q9Y365
  • 基因名：
    STARD10
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from N-terminal of Human STARD10.
  • 免疫原种属：
    Homo sapiens (Human)
  • 克隆类型：
    Polyclonal
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play metabolic roles in sperm maturation or fertilization. Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes.
  • 基因功能参考文献：
    1. Hence, we provide a molecular explanation for acquired resistance to DTX that is caused by the miR-638 deficiency and subsequent STARD10 upregulation. In consequence, alteration of miR-638/STARD10 cascade may represent an attractive strategy in future adjuvant therapy along with DTX chemotherapy. PMID: 28412359
    2. StarD10 is required for normal insulin secretion, though its deletion enhances proinsulin processing. PMID: 28132686
    3. A nonpredicted link between SNAI1-triggered EMT and the down-regulation of Nectin-1 and StarD10 through the up-regulation of miR-661, which may contribute to the invasion of breast cancer cells and poor disease outcome. PMID: 20543867
    4. Data show that in multivariate analyses incorporating tumor size, tumor grade, lymph node status, ER, PR and HER2 status, low STARD10 expression was an independent predictor of death from breast cancer. PMID: 19676041
    5. StarD10 interacts with phosphatidylcholine and phosphatidylethanolamine and preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position PMID: 15911624
    6. C-terminal StarD10 phosphorylation on serine 284 regulates its association with cellular membranes PMID: 17561512
    7. Stard10 (Sdccag28) is much more highly transcribed in mouse cardiac atria than in cardiac ventricles. PMID: 14576202

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  • 亚细胞定位：
    Cell projection, cilium, flagellum. Cytoplasm. Membrane.
  • 数据库链接：

    HGNC: 10666

    OMIM: 617382

    KEGG: hsa:10809

    STRING: 9606.ENSP00000335247

    UniGene: Hs.188606