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  4. Recombinant Human PCTP-like protein (STARD10)

Recombinant Human PCTP-like protein (STARD10)

  • 中文名称：
    人STARD10重组蛋白
  • 货号：
    CSB-YP896706HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人STARD10重组蛋白
  • 货号：
    CSB-EP896706HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人STARD10重组蛋白
  • 货号：
    CSB-EP896706HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人STARD10重组蛋白
  • 货号：
    CSB-BP896706HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人STARD10重组蛋白
  • 货号：
    CSB-MP896706HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    STARD10
  • Uniprot No.：
  • 别名：
    Antigen NY-CO-28; CGI 52; MGC14401; NY CO 28; PCTL_HUMAN; PCTP-L; PCTP-like protein; PCTP2; SDCCAG28; Serologically defined colon cancer antigen 28; StAR related lipid transfer (START) domain containing 10; StAR-related lipid transfer protein 10; StARD10; START domain containing 10; START domain-containing protein 10
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-291
  • 氨基酸序列
    MEKLAASTEP QGPRPVLGRE SVQVPDDQDF RSFRSECEAE VGWNLTYSRA GVSVWVQAVE MDRTLHKIKC RMECCDVPAE TLYDVLHDIE YRKKWDSNVI ETFDIARLTV NADVGYYSWR CPKPLKNRDV ITLRSWLPMG ADYIIMNYSV KHPKYPPRKD LVRAVSIQTG YLIQSTGPKS CVITYLAQVD PKGSLPKWVV NKSSQFLAPK AMKKMYKACL KYPEWKQKHL PHFKPWLHPE QSPLPSLALS ELSVQHADSL ENIDESAVAE SREERMGGAG GEGSDDDTSL T
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play metabolic roles in sperm maturation or fertilization. Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes.
  • 基因功能参考文献：
    1. Hence, we provide a molecular explanation for acquired resistance to DTX that is caused by the miR-638 deficiency and subsequent STARD10 upregulation. In consequence, alteration of miR-638/STARD10 cascade may represent an attractive strategy in future adjuvant therapy along with DTX chemotherapy. PMID: 28412359
    2. StarD10 is required for normal insulin secretion, though its deletion enhances proinsulin processing. PMID: 28132686
    3. A nonpredicted link between SNAI1-triggered EMT and the down-regulation of Nectin-1 and StarD10 through the up-regulation of miR-661, which may contribute to the invasion of breast cancer cells and poor disease outcome. PMID: 20543867
    4. Data show that in multivariate analyses incorporating tumor size, tumor grade, lymph node status, ER, PR and HER2 status, low STARD10 expression was an independent predictor of death from breast cancer. PMID: 19676041
    5. StarD10 interacts with phosphatidylcholine and phosphatidylethanolamine and preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18:1 or 18:2) on the sn-2 position PMID: 15911624
    6. C-terminal StarD10 phosphorylation on serine 284 regulates its association with cellular membranes PMID: 17561512
    7. Stard10 (Sdccag28) is much more highly transcribed in mouse cardiac atria than in cardiac ventricles. PMID: 14576202

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  • 亚细胞定位：
    Cell projection, cilium, flagellum. Cytoplasm. Membrane.
  • 数据库链接：

    HGNC: 10666

    OMIM: 617382

    KEGG: hsa:10809

    STRING: 9606.ENSP00000335247

    UniGene: Hs.188606