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STRA8 Antibody

  • 货号：
    CSB-PA767212LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: MCF-7 whole cell lysate, Jurkat whole cell lysate
      All lanes: STRA8 antibody at 3.4μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 37 kDa
      Observed band size: 60 kDa
    • IHC image of CSB-PA767212LA01HU diluted at 1:500 and staining in paraffin-embedded human ovarian cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) STRA8 Polyclonal antibody
  • Uniprot No.：
    Q7Z7C7
  • 基因名：
    STRA8
  • 别名：
    Stimulated by retinoic acid 8 antibody; stimulated by retinoic acid 8 homolog antibody; Stimulated by retinoic acid Gene 8 antibody; stimulated by retinoic acid gene 8 homolog antibody; Stimulated by retinoic acid gene 8 protein homolog antibody; STRA 8 antibody; STRA8 antibody; STRA8_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Stimulated by retinoic acid gene 8 protein homolog protein (115-241AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，STRA8 Antibody (CSB-PA767212LA01HU)，的标记方式是Non-conjugated。对于STRA8 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA767212LB01HU STRA8 Antibody, HRP conjugated ELISA
    FITC CSB-PA767212LC01HU STRA8 Antibody, FITC conjugated
    Biotin CSB-PA767212LD01HU STRA8 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:500-1:1000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis.
  • 基因功能参考文献：
    1. The genetic variant rs10269148 of STRA8 gene shows higher risk of spermatogenic impairment in the groups of abnormospermia than the controls PMID: 23320086
    2. Functional characterization of an homologous mouse gene. PMID: 18799751
    3. Observational study of gene-disease association. (HuGE Navigator) PMID: 20378615
    4. Expression restricted to testis (STRA8) PMID: 12489526
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 组织特异性：
    Expressed specifically in testis and fetal ovaries.
  • 数据库链接：

    HGNC: 30653

    OMIM: 609987

    KEGG: hsa:346673

    STRING: 9606.ENSP00000275764

    UniGene: Hs.592279