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  4. Recombinant Human Stimulated by retinoic acid gene 8 protein homolog (STRA8)

Recombinant Human Stimulated by retinoic acid gene 8 protein homolog (STRA8)

  • 货号：
    CSB-YP767212HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP767212HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP767212HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP767212HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP767212HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    STRA8
  • Uniprot No.：
  • 别名：
    Stimulated by retinoic acid 8; stimulated by retinoic acid 8 homolog; Stimulated by retinoic acid Gene 8; stimulated by retinoic acid gene 8 homolog; Stimulated by retinoic acid gene 8 protein homolog; STRA 8; STRA8; STRA8_HUMAN
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-330
  • 氨基酸序列
    MGKIDVDKIL FFNQEIRLWQ LIMATPEENS NPHDRATPQL PAQLQELEHR VARRRLSQAR HRATLAALFN NLRKTVYSQS DLIASKWQVL NKAKSHIPEL EQTLDNLLKL KASFNLEDGH ASSLEEVKKE YASMYSGNDS FPQNGSSPWY LNFYKQTMDL LTGSGIITPQ EAALPIVSAA ISHLWQNLSE ERKASLRQAW AQKHRGPATL AEACREPACA EGSVKDSGVD SQGASCSLVS TPEEILFEDA FDVASFLDKS EVPSTSSSSS VLASCNPENP EEKFQLYMQI INFFKGLSCA NTQVKQEASF PVDEEMIMLQ CTETFDDEDL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, acts downstream of ZGLP1 as a key effector of the meiotic program: required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. In complex with MEIOSIN, directly activates the transcription of a subset of critical meiotic genes playing a central role in cell-cycle switching from mitosis to meiosis.
  • 基因功能参考文献：
    1. The genetic variant rs10269148 of STRA8 gene shows higher risk of spermatogenic impairment in the groups of abnormospermia than the controls PMID: 23320086
    2. Functional characterization of an homologous mouse gene. PMID: 18799751
    3. Observational study of gene-disease association. (HuGE Navigator) PMID: 20378615
    4. Expression restricted to testis (STRA8) PMID: 12489526
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 组织特异性：
    Expressed specifically in testis and fetal ovaries.
  • 数据库链接：

    HGNC: 30653

    OMIM: 609987

    KEGG: hsa:346673

    STRING: 9606.ENSP00000275764

    UniGene: Hs.592279