Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. SUMF2 Antibody

SUMF2 Antibody

  • 货号：
    CSB-PA022947GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q8NBJ7
  • 基因名：
    SUMF2
  • 别名：
    SUMF2 antibody; PSEC0171 antibody; UNQ1968/PRO4500 antibody; Inactive C-alpha-formylglycine-generating enzyme 2 antibody; Paralog of formylglycine-generating enzyme antibody; pFGE antibody; Sulfatase-modifying factor 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human SUMF2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Lacks formylglycine generating activity and is unable to convert newly synthesized inactive sulfatases to their active form. Inhibits the activation of sulfatases by SUMF1.
  • 基因功能参考文献：
    1. SUMF2 interacted with IL-13 and inhibited IL-13 secretion in bronchial smooth muscle cells and lymphocytes, which was independent of IL-13 glycosylation PMID: 19739097
    2. structural analysis of human pFGE by X-ray crystallography [pFGE] PMID: 15687489
    3. pFGE (SUMF2) is the paralog of the Calpha-formylglycine-generating enzyme PMID: 15708861
    4. SUMF2 interacts with sulphatase-modifying factor 1 to regulate sulphatase activities. PMID: 15962010
    5. pFGE is retained in the ER through its C-terminal tetrapeptide PGEL, a noncanonical variant of the classic KDEL ER-retention signal. PMID: 18266766

    显示更多

    收起更多

  • 亚细胞定位：
    Endoplasmic reticulum lumen.
  • 蛋白家族：
    Sulfatase-modifying factor family
  • 组织特异性：
    Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highest levels in kidney, liver and placenta.
  • 数据库链接：

    HGNC: 20415

    OMIM: 607940

    KEGG: hsa:25870

    STRING: 9606.ENSP00000341938

    UniGene: Hs.279696