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SYNJ2BP Antibody

  • 货号：
    CSB-PA023018GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    P57105
  • 基因名：
    SYNJ2BP
  • 别名：
    SYNJ2BP antibody; OMP25 antibody; Synaptojanin-2-binding protein antibody; Mitochondrial outer membrane protein 25 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human SYNJ2BP
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
  • 基因功能参考文献：
    1. Data found that SYNJ2BP was decreased in hepatocellular carcinoma (HCC) tissues and cell lines and provide evidence that SYNJ2BP may act as a tumor suppressor during HCC development activating DLL4 pathway. PMID: 27440153
    2. Ubiquilins are a family of chaperones for cytosolically exposed transmembrane domains and use ubiquitin to triage clients, like Omp25, for degradation via coordinated intra- and intermolecular interactions. PMID: 27345149
    3. These results suggest that ARIP2 is a putative growth-promoting factor involved in breast tumorigenesis and tumor development. PMID: 19349195
  • 亚细胞定位：
    Mitochondrion outer membrane.
  • 数据库链接：

    HGNC: 18955

    OMIM: 609411

    KEGG: hsa:55333

    STRING: 9606.ENSP00000256366

    UniGene: Hs.443661