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SYNJ2BP Antibody

  • 货号：
    CSB-PA023018LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunoprecipitating SYNJ2BP in Rat kidney tissue
      Lane 1: Rabbit control IgG instead of CSB-PA023018LA01HU in Rat kidney tissue. For western blotting, a HRP-conjugated light chain specific antibody was used as the secondary antibody (1/50000)
      Lane 2: CSB-PA023018LA01HU (6µg) + Rat kidney tissue (500µg)
      Lane 3: Rat kidney tissue (20µg)
    • Western blot
      All lanes: SYNJ2BP antibody at 3µg/ml
      Lane 1: MCF-7 whole cell lysate
      Lane 2: U251 whole cell lysate
      Lane 3: Caco-2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 16 kDa
      Observed band size: 16 kDa

       
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA023018LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA023018LA01HU at dilution of 1:100
    • Western Blot
      Positive WB detected in: Rat kidney tissue
      All lanes: SYNJ2BP antibody at 2.8μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 16 kDa
      Observed band size: 16 kDa
    • Immunohistochemistry analysis of human liver cancer using CSB-PA023018LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) SYNJ2BP Polyclonal antibody
  • Uniprot No.：
    P57105
  • 基因名：
    SYNJ2BP
  • 别名：
    SYNJ2BP antibody; OMP25 antibody; Synaptojanin-2-binding protein antibody; Mitochondrial outer membrane protein 25 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Rat
  • 免疫原：
    Recombinant Human Synaptojanin-2-binding protein (1-117AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，SYNJ2BP Antibody (CSB-PA023018LA01HU)，的标记方式是Non-conjugated。对于SYNJ2BP Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA023018LB01HU SYNJ2BP Antibody, HRP conjugated ELISA
    FITC CSB-PA023018LC01HU SYNJ2BP Antibody, FITC conjugated
    Biotin CSB-PA023018LD01HU SYNJ2BP Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC, IP
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IP 1:200-1:2000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulates endocytosis of activin type 2 receptor kinases through the Ral/RALBP1-dependent pathway and may be involved in suppression of activin-induced signal transduction.
  • 基因功能参考文献：
    1. Data found that SYNJ2BP was decreased in hepatocellular carcinoma (HCC) tissues and cell lines and provide evidence that SYNJ2BP may act as a tumor suppressor during HCC development activating DLL4 pathway. PMID: 27440153
    2. Ubiquilins are a family of chaperones for cytosolically exposed transmembrane domains and use ubiquitin to triage clients, like Omp25, for degradation via coordinated intra- and intermolecular interactions. PMID: 27345149
    3. These results suggest that ARIP2 is a putative growth-promoting factor involved in breast tumorigenesis and tumor development. PMID: 19349195
  • 亚细胞定位：
    Mitochondrion outer membrane.
  • 数据库链接：

    HGNC: 18955

    OMIM: 609411

    KEGG: hsa:55333

    STRING: 9606.ENSP00000256366

    UniGene: Hs.443661