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TBCC Antibody

  • 货号：
    CSB-PA023227LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: TBCC antibody at 2µg/ml
      Lane 1: Hela whole cell lysate
      Lane 2: HepG2 whole cell lysate
      Lane 3: A549 whole cell lysate
      Lane 4: MCF-7 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 40 kDa
      Observed band size: 40 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA023227LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA023227LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) TBCC Polyclonal antibody
  • Uniprot No.：
    Q15814
  • 基因名：
    TBCC
  • 别名：
    Beta tubulin cofactor C antibody; CFC antibody; TBCC antibody; TBCC_HUMAN antibody; Tubulin folding cofactor C antibody; Tubulin specific chaperone c antibody; Tubulin-folding cofactor C antibody; Tubulin-specific chaperone C antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Tubulin-specific chaperone C protein (2-346AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，TBCC Antibody (CSB-PA023227LA01HU)，的标记方式是Non-conjugated。对于TBCC Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA023227LB01HU TBCC Antibody, HRP conjugated ELISA
    FITC CSB-PA023227LC01HU TBCC Antibody, FITC conjugated
    Biotin CSB-PA023227LD01HU TBCC Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Tubulin-folding protein; involved in the final step of the tubulin folding pathway.
  • 基因功能参考文献：
    1. a testable model for TBCC N-terminal domain/tubulin recognition in which the highly charged N-terminus as well as residues from the three helices and the loops interact with the acidic hypervariable regions of tubulin monomers PMID: 22028797
    2. Microtubule dynamicity was reduced in breast cancer cells overexpressing TBCC. Cell cycle distribution was altered in cells containing larger amounts of TBCC. TBCC had little effect on cell proliferation. PMID: 20384997
    3. functional overlap with retinitis pigmenosa 2 protein PMID: 11847227
  • 亚细胞定位：
    Cytoplasm. Note=Detected predominantly in the photoreceptor connecting cilium.
  • 蛋白家族：
    TBCC family
  • 组织特异性：
    Expressed in the retina. Expressed in the rod and cone photoreceptors, extending from the inner segments (IS), through the outer nuclear layer (ONL) and into the synapses in the outer plexiform layer (OPL). Strongly expressed to the photoreceptor connecti
  • 数据库链接：

    HGNC: 11580

    OMIM: 602971

    KEGG: hsa:6903

    STRING: 9606.ENSP00000244625

    UniGene: Hs.75064