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TBCC Antibody

  • 货号：
    CSB-PA023227GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q15814
  • 基因名：
    TBCC
  • 别名：
    Beta tubulin cofactor C antibody; CFC antibody; TBCC antibody; TBCC_HUMAN antibody; Tubulin folding cofactor C antibody; Tubulin specific chaperone c antibody; Tubulin-folding cofactor C antibody; Tubulin-specific chaperone C antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human TBCC
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Tubulin-folding protein; involved in the final step of the tubulin folding pathway.
  • 基因功能参考文献：
    1. a testable model for TBCC N-terminal domain/tubulin recognition in which the highly charged N-terminus as well as residues from the three helices and the loops interact with the acidic hypervariable regions of tubulin monomers PMID: 22028797
    2. Microtubule dynamicity was reduced in breast cancer cells overexpressing TBCC. Cell cycle distribution was altered in cells containing larger amounts of TBCC. TBCC had little effect on cell proliferation. PMID: 20384997
    3. functional overlap with retinitis pigmenosa 2 protein PMID: 11847227
  • 亚细胞定位：
    Cytoplasm. Note=Detected predominantly in the photoreceptor connecting cilium.
  • 蛋白家族：
    TBCC family
  • 组织特异性：
    Expressed in the retina. Expressed in the rod and cone photoreceptors, extending from the inner segments (IS), through the outer nuclear layer (ONL) and into the synapses in the outer plexiform layer (OPL). Strongly expressed to the photoreceptor connecti
  • 数据库链接：

    HGNC: 11580

    OMIM: 602971

    KEGG: hsa:6903

    STRING: 9606.ENSP00000244625

    UniGene: Hs.75064