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TDRKH Antibody

  • 中文名称：
    TDRKH兔多克隆抗体
  • 货号：
    CSB-PA023362GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y2W6
  • 基因名：
    TDRKH
  • 别名：
    2700091C21Rik antibody; Putative RNA binding protein antibody; RGD1311196 antibody; RP11-98D18.8 antibody; TDRD2 antibody; TDRD7 antibody; Tdrkh antibody; TDRKH_HUMAN antibody; Tudor and KH domain containing antibody; Tudor and KH domain-containing protein antibody; tudor domain containing 2 antibody; Tudor domain-containing protein 2 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human TDRKH
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Participates in the primary piRNA biogenesis pathway and is required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for the final steps of primary piRNA biogenesis by participating in the processing of 31-37 nt intermediates into mature piRNAs. May act in pi-bodies and piP-bodies by transferring piRNA precursors or intermediates to or between these granules.
  • 基因功能参考文献：
    1. Unlike most other Tudor domains TDRD2 preferentially recognizes an unmethylated arginine-rich sequence from PIWIL1. PMID: 29118143
    2. Tudor domain proteins interact with arginine-glycine-rich motifs in a methylarginine-dependent manner. PMID: 15955813
  • 亚细胞定位：
    Cytoplasm. Mitochondrion.
  • 蛋白家族：
    Tdrkh family
  • 数据库链接：

    HGNC: 11713

    OMIM: 609501

    KEGG: hsa:11022

    STRING: 9606.ENSP00000357812

    UniGene: Hs.144439