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  4. TEX11 Antibody

TEX11 Antibody

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  • 中文名称：
    TEX11兔多克隆抗体
  • 货号：
    CSB-PA023401GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q8IYF3
  • 基因名：
    TEX11
  • 别名：
    TEX11 antibody; Testis-expressed protein 11 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Human TEX11
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Regulator of crossing-over during meiosis. Involved in initiation and/or maintenance of chromosome synapsis and formation of crossovers.
  • 基因功能参考文献：
    1. Through the translational regulation of novel RNA targets SMC1B and TEX11, DAZL may have a key role in regulating chromosome cohesion and DNA recombination; two processes fundamental in determining oocyte quality and whose establishment in foetal life may support lifelong fertility. PMID: 28364521
    2. Genetic screening of a large cohort of idiopathic infertile men reveals that TEX11 mutations, including frameshift and splicing acceptor site mutations, cause infertility in 1% of azoospermic men. PMID: 26136358
    3. TEX11 mutations, including frameshift and splicing acceptor site mutations, cause infertility in 1% of non-obstructive azoospermic men. PMID: 26136358
    4. hemizygous TEX11 mutations were a common cause of meiotic arrest and azoospermia in infertile men PMID: 25970010
    5. TEX11 was specifically expressed in human testis. PMID: 11279525

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  • 相关疾病：
    Spermatogenic failure, X-linked, 2 (SPGFX2)
  • 亚细胞定位：
    Chromosome.
  • 蛋白家族：
    SPO22 family
  • 组织特异性：
    Testis-specific. Not expressed in adult ovaries.
  • 数据库链接：

    HGNC: 11733

    OMIM: 300311

    KEGG: hsa:56159

    STRING: 9606.ENSP00000340995

    UniGene: Hs.121776