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TOE1 Antibody

  • 中文名称：
    TOE1兔多克隆抗体
  • 货号：
    CSB-PA024041GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q96GM8
  • 基因名：
    TOE1
  • 别名：
    Target of EGR1 protein 1 antibody; target of EGR1; member 1 antibody; Toe1 antibody; TOE1_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human TOE1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Inhibits cell growth rate and cell cycle. Induces CDKN1A expression as well as TGF-beta expression. Mediates the inhibitory growth effect of EGR1. Involved in the maturation of snRNAs and snRNA 3'-tail processing.
  • 基因功能参考文献：
    1. Human cells with reduced levels of TOE1 accumulated 3'-end-extended pre-snRNA. PMID: 28092684
    2. Antiviral potency of TOE1 and its cell-penetrating capability have been identified to lie within a 35-amino-acid region containing the nuclear localization sequence PMID: 26056259
    3. TOE1 has a role in the growth inhibitory activity of Egr1 PMID: 12562764
  • 相关疾病：
    Pontocerebellar hypoplasia 7 (PCH7)
  • 亚细胞定位：
    Nucleus, nucleolus. Nucleus speckle. Note=Localizes to nuclear speckles.
  • 蛋白家族：
    CAF1 family
  • 组织特异性：
    Widely expressed.
  • 数据库链接：

    HGNC: 15954

    OMIM: 613931

    KEGG: hsa:114034

    STRING: 9606.ENSP00000361162

    UniGene: Hs.525091