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TRAF3IP3 Antibody

  • 货号：
    CSB-PA112350
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA112350(TRAF3IP3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cells, Primary antibody: CSB-PA112350(TRAF3IP3 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y228
  • 基因名：
    TRAF3IP3
  • 别名：
    TRAF3IP3 antibody; T3JAM antibody; TRAF3-interacting JNK-activating modulator antibody; TRAF3-interacting protein 3 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Fusion protein of Human TRAF3IP3
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:15-1:50
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Adapter protein that plays essential roles in both innate and adaptive immunity. Plays a crucial role in the regulation of thymocyte development. Mechanistically, mediates TCR-stimulated activation through recruiting MAP2K1/MEK1 to the Golgi and, thereby, facilitating the interaction of MAP2K1/MEK1 with its activator BRAF. Plays also an essential role in regulatory T-cell stability and function by recruiting the serine-threonine phosphatase catalytic subunit (PPP2CA) to the lysosome, thereby facilitating the interaction of PP2Ac with the mTORC1 component RPTOR and restricting glyc...显示更多
  • 基因功能参考文献：
    1. This paper provides an alignment of the mouse and human proteins. PMID: 14572659
    2. TRAF3IP3 stimulated cell growth by modulating the c-Jun N-terminal kinase (JNK) pathway PMID: 17868742
  • 亚细胞定位：
    Cell membrane. Golgi apparatus membrane; Single-pass type IV membrane protein. Lysosome membrane. Mitochondrion outer membrane.
  • 数据库链接：

    HGNC: 30766

    OMIM: 608255

    KEGG: hsa:80342

    STRING: 9606.ENSP00000355991

    UniGene: Hs.147434