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TRIM47 Antibody

  • 中文名称：
    TRIM47兔多克隆抗体
  • 货号：
    CSB-PA103770
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA103770(TRIM47 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA103770(TRIM47 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他：

产品详情

  • Uniprot No.：
    Q96LD4
  • 基因名：
    TRIM47
  • 别名：
    TRIM47 antibody; GOA antibody; RNF100 antibody; E3 ubiquitin-protein ligase TRIM47 antibody; EC 2.3.2.27 antibody; Gene overexpressed in astrocytoma protein antibody; RING finger protein 100 antibody; Tripartite motif-containing protein 47 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human TRIM47
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    IHC 1:10-1:50
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    E3 ubiquitin-protein ligase that mediates the ubiquitination and proteasomal degradation of CYLD.
  • 基因功能参考文献：
    1. Study shows that protein and gene expression level of TRIM47 are up-regulated in prostate neoplasm. PMID: 26873435
    2. High TRIM47 expression is associated with non-small cell lung carcinoma. PMID: 28186994
    3. These results suggest that rs1055129 in TRIM47 is not associated with leukoaraiosis (LA) risk in the Chinese population. However, the association of rs1055129 (TRIM47) with LA before Bonferroni correction and Sidak correction is worth highlighting. PMID: 27583843
  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    TRIM/RBCC family
  • 组织特异性：
    Low expression in most tissues. Higher expression in kidney tubular cells. Overexpressed in astrocytoma tumor cells.
  • 数据库链接：

    HGNC: 19020

    OMIM: 611041

    KEGG: hsa:91107

    STRING: 9606.ENSP00000254816

    UniGene: Hs.293660