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UBLCP1 Antibody

  • 货号：
    CSB-PA025504GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q8WVY7
  • 基因名：
    UBLCP1
  • 别名：
    CPUB1 antibody; CTD like phosphatase domain containing protein antibody; CTD phosphatase like with ubiquitin domain 1 antibody; FLJ25267 antibody; MGC10067 antibody; Nuclear proteasome inhibitor UBLCP1 antibody; UBCP1_HUMAN antibody; Ubiquitin like domain containing CTD phosphatase 1 antibody; Ubiquitin-like domain-containing CTD phosphatase 1 antibody; UBLCP1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human UBLCP1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.
  • 基因功能参考文献：
    1. Data show that UBLCP1 selectively binds to the 26S proteasome non-ATPase regulatory subunit 13 (19S regulatory particle) in regulating proteasome assembly. PMID: 28539385
    2. the high-resolution solution structure of the UBL domain of human UBLCP1 and its interaction with Rpn1 PMID: 23667555
    3. UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity PMID: 21949367
  • 亚细胞定位：
    Nucleus. Note=Colocalizes with nuclear proteasomes.
  • 组织特异性：
    Broadly expressed, with highest levels in placenta, lung, testis and ovary. Up-regulated in tumor tissues.
  • 数据库链接：

    HGNC: 28110

    OMIM: 609867

    KEGG: hsa:134510

    STRING: 9606.ENSP00000296786

    UniGene: Hs.591733