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  4. UGP2 Antibody

UGP2 Antibody

  • 中文名称：
    UGP2兔多克隆抗体
  • 货号：
    CSB-PA025569GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q16851
  • 基因名：
    UGP2
  • 别名：
    pHC379 antibody; UDP glucose diphosphorylase antibody; UDP glucose pyrophosphorylase 1 antibody; UDP glucose pyrophosphorylase 2 antibody; UDP glucose pyrophosphorylase antibody; UDP-glucose pyrophosphorylase antibody; UDPG antibody; UDPGP 2 antibody; UDPGP antibody; UDPGP2 antibody; UGP 1 antibody; UGP 2 antibody; UGP1 antibody; Ugp2 antibody; UGPA_HUMAN antibody; UGPase 2 antibody; UGPase antibody; UGPP 1 antibody; UGPP 2 antibody; UGPP1 antibody; UGPP2 antibody; Uridyl diphosphate glucose pyrophosphorylase 1 antibody; Uridyl diphosphate glucose pyrophosphorylase 2 antibody; UTP glucose 1 phosphate uridyltransferase antibody; UTP glucose 1 phosphate uridylyltransferase 2 antibody; UTP glucose 1 phosphate uridylyltransferase antibody; UTP--glucose-1-phosphate uridylyltransferase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Human UGP2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.
  • 基因功能参考文献：
    1. High UGP2 expression is associated with malignant pancreatic lesions. PMID: 29347944
    2. This study provides clear evidence that the octameric state is a prerequisite for activity in the uridine diphosphate-glucose pyrophosphorylase. PMID: 23254995
    3. The crystal structure was determined and shown to form octamers through end-to-end and side-by-side interactions. Mutagenesis studies showed that both dissociation of octamers and mutations of the latch loop can significantly affect the activity. PMID: 22132858
    4. GYS1 regulation by HIF plays a central role in the hypoxic accumulation of glycogen, and hypoxia also upregulates the expression of UTP:glucose-1-phosphate urydylyltransferase (UGP2) and 1,4-alpha glucan branching enzyme (GBE1) PMID: 20300197
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    UDPGP type 1 family
  • 组织特异性：
    Highly expressed in various brain regions. Expressed in amygdala, anterior cingulate cortex, caudate, cerebellar hemisphere, cerebellum, cortex, frontal cortex, hippocampus, hypothalamus, nucleus accumbens, putamen, spinal cord and substantia nigra. Also
  • 数据库链接：

    HGNC: 12527

    OMIM: 191750

    KEGG: hsa:7360

    STRING: 9606.ENSP00000338703

    UniGene: Hs.516217