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ULK4 Antibody

  • 货号：
    CSB-PA853394ESR1HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA853394ESR1HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ULK4 Polyclonal antibody
  • Uniprot No.：
    Q96C45
  • 基因名：
    ULK4
  • 别名：
    DKFZp 434E1822 antibody; DKFZp434E1822 antibody; FAM 7 C 1 antibody; FAM7C1 antibody; FLJ 20574 antibody; FLJ20574 antibody; REC 01035 antibody; REC01035 antibody; Serine/threonine-protein kinase ULK4 antibody; ULK 4 antibody; ULK4 antibody; ULK4_HUMAN antibody; Unc 51 like kinase 4 antibody; Unc 51 like kinase 4 (C. elegans) antibody; Unc-51-like kinase 4 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Serine/threonine-protein kinase ULK4 protein (1-290AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in the remodeling of cytoskeletal components, such as alpha-tubulin, and in this way regulates neurite branching and elongation, as well as cell motility.
  • 基因功能参考文献：
    1. results indicate that genetic variations in LRP1 and ULK4 contribute to risk for presenting with an acute aortic dissection PMID: 27569546
    2. Our findings indicate that ULK4 is a rare susceptibility gene for schizophrenia. PMID: 24284070
    3. First identified as an ULK family kinase and predicted to be catalytically inactive. PMID: 12471243
    4. Single-nucleotide polymorphism rs1052501 in ULK4 gene is associated with monoclonal gammopathy of undetermined significance and multiple myeloma PMID: 22945773
  • 相关疾病：
    Various anomalies in ULK4 gene have been reported for several cases of schizophrenia, schizophrenia plus bipolar disorder and autism. ULK4 gene has been proposed to be a rare susceptibility risk factor for a range of psychiatric diseases including schizophrenia.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily
  • 组织特异性：
    Expressed in the brain, mainly in postmitotic neurons, including GABAergic neurons, but not in astrocytes (at protein level).
  • 数据库链接：

    HGNC: 15784

    OMIM: 617010

    KEGG: hsa:54986

    STRING: 9606.ENSP00000301831

    UniGene: Hs.656192