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  4. Recombinant Human Serine/threonine-protein kinase ULK4 (ULK4)

Recombinant Human Serine/threonine-protein kinase ULK4 (ULK4)

  • 中文名称：
    人ULK4重组蛋白
  • 货号：
    CSB-YP853394HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人ULK4重组蛋白
  • 货号：
    CSB-EP853394HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人ULK4重组蛋白
  • 货号：
    CSB-EP853394HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人ULK4重组蛋白
  • 货号：
    CSB-BP853394HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人ULK4重组蛋白
  • 货号：
    CSB-MP853394HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ULK4
  • Uniprot No.：
  • 别名：
    DKFZp 434E1822; DKFZp434E1822; FAM 7 C 1; FAM7C1; FLJ 20574; FLJ20574; REC 01035; REC01035; Serine/threonine-protein kinase ULK4; ULK 4; ULK4; ULK4_HUMAN; Unc 51 like kinase 4; Unc 51 like kinase 4 (C. elegans); Unc-51-like kinase 4
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May be involved in the remodeling of cytoskeletal components, such as alpha-tubulin, and in this way regulates neurite branching and elongation, as well as cell motility.
  • 基因功能参考文献：
    1. results indicate that genetic variations in LRP1 and ULK4 contribute to risk for presenting with an acute aortic dissection PMID: 27569546
    2. Our findings indicate that ULK4 is a rare susceptibility gene for schizophrenia. PMID: 24284070
    3. First identified as an ULK family kinase and predicted to be catalytically inactive. PMID: 12471243
    4. Single-nucleotide polymorphism rs1052501 in ULK4 gene is associated with monoclonal gammopathy of undetermined significance and multiple myeloma PMID: 22945773
  • 相关疾病：
    Various anomalies in ULK4 gene have been reported for several cases of schizophrenia, schizophrenia plus bipolar disorder and autism. ULK4 gene has been proposed to be a rare susceptibility risk factor for a range of psychiatric diseases including schizophrenia.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily
  • 组织特异性：
    Expressed in the brain, mainly in postmitotic neurons, including GABAergic neurons, but not in astrocytes (at protein level).
  • 数据库链接：

    HGNC: 15784

    OMIM: 617010

    KEGG: hsa:54986

    STRING: 9606.ENSP00000301831

    UniGene: Hs.656192