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VWA5A Antibody

  • 货号：
    CSB-PA025954LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: VWA5A antibody at 1µg/ml
      Lane 1: A549 whole cell lysate
      Lane 2: MCF-7 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 87, 48, 46, 30 kDa
      Observed band size: 87 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) VWA5A Polyclonal antibody
  • Uniprot No.：
    O00534
  • 基因名：
    VWA5A
  • 别名：
    VWA5A antibody; BCSC1 antibody; LOH11CR2A antibody; von Willebrand factor A domain-containing protein 5A antibody; Breast cancer suppressor candidate 1 antibody; BCSC-1 antibody; Loss of heterozygosity 11 chromosomal region 2 gene A protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human von Willebrand factor A domain-containing protein 5A protein (1-415AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，VWA5A Antibody (CSB-PA025954LA01HU)，的标记方式是Non-conjugated。对于VWA5A Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA025954LB01HU VWA5A Antibody, HRP conjugated ELISA
    FITC CSB-PA025954LC01HU VWA5A Antibody, FITC conjugated
    Biotin CSB-PA025954LD01HU VWA5A Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.
  • 基因功能参考文献：
    1. BCSC-1 binds to Sox10, which down regulates MITF, and results in a switch of melanoma cells from a proliferative to a migratory phenotype. PMID: 22594792
    2. LOH11CR2A, PIG8 and CHEK1 are candidate tumor suppressor genes associated with breast carcinoma and have significant clinical as well as prognostic importance. PMID: 21803008
    3. BCSC-1 suppression might play roles in tumorigenesis of some nasopharyngeal carcinomas PMID: 19656157
  • 组织特异性：
    Expressed at low level in many tissues. Not expressed in 80% of tumor cell lines tested.
  • 数据库链接：

    HGNC: 6658

    OMIM: 602929

    KEGG: hsa:4013

    STRING: 9606.ENSP00000376504

    UniGene: Hs.152944