Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. WDR91 Antibody

WDR91 Antibody

  • 货号：
    CSB-PA026077LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA026077LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA026077LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) WDR91 Polyclonal antibody
  • Uniprot No.：
    A4D1P6
  • 基因名：
    WDR91
  • 别名：
    HSPC049 antibody; WD repeat containing protein 91 antibody; WD repeat domain 91 antibody; WD repeat-containing protein 91 antibody; WDR 91 antibody; WDR91 antibody; WDR91_HUMAN antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human WD repeat-containing protein 91 protein (1-747AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，WDR91 Antibody (CSB-PA026077LA01HU)，的标记方式是Non-conjugated。对于WDR91 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA026077LB01HU WDR91 Antibody, HRP conjugated ELISA
    FITC CSB-PA026077LC01HU WDR91 Antibody, FITC conjugated
    Biotin CSB-PA026077LD01HU WDR91 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport. It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome. May play a role in meiosis.
  • 基因功能参考文献：
    1. suggest a role for the WDR81-WDR91 complex in the fusion of endolysosomal compartments and the absence of WDR81 leads to impaired receptor trafficking and degradation PMID: 27126989
    2. WDR91 serves as a Rab7 effector that is essential for neuronal development by facilitating endosome conversion in the endosome-lysosome pathway. PMID: 28860274
  • 亚细胞定位：
    Early endosome membrane; Peripheral membrane protein. Late endosome membrane.
  • 蛋白家族：
    WD repeat WDR91 family
  • 数据库链接：

    HGNC: 24997

    KEGG: hsa:29062

    STRING: 9606.ENSP00000346466

    UniGene: Hs.459858