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ZKSCAN4 Antibody

  • 货号：
    CSB-PA005456
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of MCF7 HepG2 293 mouse brain mouse lung cells using ZKSCAN4 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q969J2
  • 基因名：
    ZKSCAN4
  • 别名：
    FLJ32136 antibody; P1P373C6 antibody; p373c6.1 (novel C2H2 type zinc finger protein) antibody; P373c6.1 antibody; Zinc finger protein 307 antibody; Zinc finger protein 427 antibody; Zinc finger protein with KRAB and SCAN domains 4 antibody; Zinc finger with KRAB and SCAN domains 4 antibody; ZKSC4_HUMAN antibody; ZKSCAN4 antibody; ZNF427 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human ZKSCAN4.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May be involved in the transcriptional activation of MDM2 and EP300 genes.
  • 基因功能参考文献：
    1. our results indicate that ZNF307 may serve as a tumor suppressor and inhibits cell proliferation of hepatocellular carcinoma via inducing apoptosis PMID: 28765950
    2. ZNF307 ameliorates pressure overload-induced cardiac hypertrophy by inhibiting the activity of NF-kappaB-signaling pathway PMID: 28223477
    3. ZNF307 might suppress p53-p21 pathway through activating MDM2 and EP300 expression and inducing p53 degradation PMID: 17910948
    4. The SCAN- and KRAB-domain-containing zinc finger protein 307 (ZKSCAN4) was co-precipitated with the receptor when both proteins were overexpressed in HEK293 cells. PMID: 19008334
  • 亚细胞定位：
    Nucleus.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 组织特异性：
    Expressed in adult heart, brain, placenta, lung and kidney, but not in adult liver and skeletal muscle. In 17-day old embryo, detected in liver, skeletal muscle, brain, heart and small intestine.
  • 数据库链接：

    HGNC: 13854

    OMIM: 611643

    KEGG: hsa:387032

    STRING: 9606.ENSP00000366509

    UniGene: Hs.44720