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gag-pol Antibody

  • 中文名称:
    gag-pol兔多克隆抗体
  • 货号:
    CSB-PA361030XA01MHK
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: gag-pol antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 23.2 kDa
      Observed band size: 26 kDa
  • 其他:

产品详情

  • Uniprot No.:
    P03355
  • 基因名:
    gag-pol
  • 别名:
    Gag-Pol polyprotein (Pr180gag-pol) [Cleaved into: Matrix protein p15 (MA); RNA-binding phosphoprotein p12 (pp12); Capsid protein p30 (CA); Nucleocapsid protein p10 (NC-pol); Protease p14 (PR) (EC 3.4.23.-); Reverse transcriptase/ribonuclease H p80 (RT) (EC 2.7.7.49) (EC 2.7.7.7) (EC 3.1.26.4); Integrase p46 (IN) (EC 2.7.7.-) (EC 3.1.-.-)] gag-pol
  • 反应种属:
    Moloney murine leukemia virus (isolate Shinnick) (MoMLV)
  • 免疫原:
    Recombinant Moloney murine leukemia virus (isolate Shinnick) (MoMLV) POL protein (1444-1738aa)
  • 免疫原种属:
    Moloney murine leukemia virus (isolate Shinnick) (MoMLV)
  • 标记方式:
    Non-conjugated
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    Protein G
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, WB
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag-Pol, or to Gag-Pol binding host factors. Interaction with HECT ubiquitin ligases probably links the viral protein to the host ESCRT pathway and facilitates release.; Targets Gag and gag-pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear lo...显示更多
  • 基因功能参考文献:
    1. Findings indicate that reverse transcriptase is a relatively passive enzyme, able to polymerize on structured templates by exploiting their thermal breathing. PMID: 29165701
    2. X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition has been reported. PMID: 28066922
    3. transmembrane protein associates with the assembling core particle through the R-peptide before budding and that this is the mechanism by which the budding virus acquires the envelope proteins. [TM R-peptide] PMID: 16690922
    4. analysis of how the murine leukaemia virus Env opens for membrane fusion PMID: 18800055
  • 亚细胞定位:
    [Gag-Pol polyprotein]: Virion. Host cell membrane; Lipid-anchor. Host late endosome membrane; Lipid-anchor. Host endosome, host multivesicular body.; [Matrix protein p15]: Virion.; [Capsid protein p30]: Virion.; [Nucleocapsid protein p10-Pol]: Virion.; [Protease]: Virion.; [RNA-binding phosphoprotein p12]: Host cytoplasm.
  • 数据库链接:

    KEGG: vg:2193424