产品详情
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产品描述:
The rgpB polyclonal antibody is produced by injecting rabbits with the recombinant Porphyromonas gingivalis Gingipain R2 protein (230-473aa), which serves as the immunogen. The rabbits then produce antibodies against the Porphyromonas gingivalis rgpB antigen. These antibodies are purified from the rabbit serum using protein G purification. The purity is 95%+. The resulting purified rabbit anti-Porphyromonas gingivalis rgpB polyclonal antibody is highly specific to Porphyromonas gingivalis rgpB and has a high affinity for the antigen. This rgpB antibody is suitable for use in ELISA.
The rgpB protein mainly degrades and modifies host proteins, particularly those involved in the immune response, to facilitate the survival of P. gingivalis within the host. It also plays a role in the regulation of gene expression in P. gingivalis and the induction of tissue destruction and bone resorption associated with periodontitis.
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产品名称:Rabbit anti-Porphyromonas gingivalis rgpB Polyclonal antibody
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Uniprot No.:P95493
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基因名:rgpB
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别名:rgpB antibody; prtRII antibody; rgp2 antibody; PG_0506Gingipain R2 antibody; EC 3.4.22.37 antibody; Arg-gingipain antibody; Gingipain 2 antibody; RGP-2 antibody
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宿主:Rabbit
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反应种属:Porphyromonas gingivalis
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免疫原:Recombinant Porphyromonas gingivalis Gingipain R2 protein (230-473AA)
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免疫原种属:Porphyromonas gingivalis
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标记方式:Non-conjugated
本页面中的产品,rgpB Antibody (CSB-PA310587LA01EYA),的标记方式是Non-conjugated。对于rgpB Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
引用文献
- Comparative analysis of Porphyromonas gingivalis A7436 and ATCC 33277 strains reveals differences in the expression of heme acquisition systems W Du,Microbiology spectrum,2024
- Interplay between Porphyromonas gingivalis Hemophore-Like Protein HmuY and Kgp/RgpA Gingipains Plays a Superior Role in Heme Supply M Śmiga,Microbiology spectrum,2023
相关产品
靶点详情
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功能:Thiol protease. Acts synergistically with RgpA to catalyze the maturation of fimbrial subunits, such as FimA. Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms.
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亚细胞定位:Secreted.
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蛋白家族:Peptidase C25 family
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数据库链接:
KEGG: pgi:PG_0506
STRING: 242619.PG0506
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