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stau Antibody

  • 中文名称：
    stau兔多克隆抗体
  • 货号：
    CSB-PA329523XA01DLU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: recombinant protein
      All lanes: stau Antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 34 kDa
      Observed band size: 34 kDa
  • 其他：

产品详情

  • Uniprot No.：
    P25159
  • 基因名：
    stau
  • 别名：
    Maternal effect protein staufen stau CG5753
  • 反应种属：
    Drosophila melanogaster (Fruit fly)
  • 免疫原：
    Recombinant Drosophila melanogaster (Fruit fly) stau protein (321-582aa)
  • 免疫原种属：
    Drosophila melanogaster (Fruit fly)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Affinity-chromatography
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    RNA-binding protein which forms ribonucleoprotein complexes (RNPs) that play critical roles in the localization, translational repression and turnover of RNAs during embryogenesis, neurotransmission and neurogenesis. In the oocyte, essential for the localization of both the osk/oskar mRNA to the posterior pole and bcd/bicoid RNA to the anterior pole, and is therefore required for the correct anterior-posterior patterning of the developing embryo. Association with osk or bcd at their respective poles, appears to promote the formation and stabilization of the ribonucleoprotein complexes. Integral component of diverse neuritic ribonucleoprotein complexes (RNPs) that mediate the transport, translation and turnover of neuronal RNAs during neuorgenesis and the translation repression of synaptic transcripts in preparation for their dendritic targeting.
  • 基因功能参考文献：
    1. The role of Miranda in the localization of Staufen during the division of neuroblasts is described. PMID: 26423004
    2. Staufen targets coracle mRNA to Drosophila neuromuscular junctions and regulates GluRIIA synaptic accumulation and bouton number. PMID: 24951879
    3. establishment of developmental precision and proportions in the early Drosophila embryo PMID: 11845210
    4. role in long-term memory PMID: 12593794
    5. Miranda has a role in coupling oskar mRNA/Staufen complexes to the bicoid mRNA localization pathway PMID: 16905128

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  • 亚细胞定位：
    Cytoplasm, Cytoplasmic ribonucleoprotein granule.
  • 组织特异性：
    Polar granules at the posterior pole of the oocyte, and by the time the egg is laid, at the anterior pole.
  • 数据库链接：

    KEGG: dme:Dmel_CG5753

    STRING: 7227.FBpp0085962

    UniGene: Dm.4722