TMEM192 Recombinant Monoclonal Antibody
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货号:CSB-RA249639A0HU
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规格:¥1320
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图片:
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其他:
产品详情
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Uniprot No.:Q8IY95
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基因名:TMEM192
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别名:Transmembrane protein 192, TMEM192
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反应种属:Human
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免疫原:A synthesized peptide derived from human TMEM192
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
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克隆类型:Monoclonal
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抗体亚型:Rabbit IgG
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纯化方式:Affinity-chromatography
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克隆号:21G8
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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产品提供形式:Liquid
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应用范围:ELISA, WB, IHC
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推荐稀释比:
Application Recommended Dilution WB 1:500-1:2000 IHC 1:50-1:200 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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基因功能参考文献:
- s found that transmembrane protein 192 (TMEM192) interacted with TIG1. s also found that both TIG1A and TIG1B isoforms interacted and co-localized with TMEM192 in HtTA cervical cancer cells. The expression of TIG1 induced the expression of autophagy-related proteins. PMID: 27989102
- TMEM192 deficiency can induce autophagy in tumor cells, and can further activate apoptosis by the mitochondrial pathway through autophagy. PMID: 22736246
- TMEM192 was found to be strongly expressed in human kidney, liver, lung and pancreas tissue. The widespread tissue distribution could suggest an important role of TMEM192 for lysosomal function. PMID: 20370317
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亚细胞定位:Lysosome membrane; Multi-pass membrane protein. Late endosome.
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蛋白家族:TMEM192 family
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组织特异性:Strongly expressed in kidney, liver, lung and pancreas.
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数据库链接:
HGNC: 26775
KEGG: hsa:201931
STRING: 9606.ENSP00000305069
UniGene: Hs.704511