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  4. Recombinant Arabidopsis thaliana Serine/threonine-protein kinase AtPK1/AtPK6 (ATPK1)

Recombinant Arabidopsis thaliana Serine/threonine-protein kinase AtPK1/AtPK6 (ATPK1)

  • 中文名称：
    Recombinant Arabidopsis thaliana Serine/threonine-protein kinase AtPK1/AtPK6(ATPK1),Yeast
  • 货号：
    CSB-YP337226DOA
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Serine/threonine-protein kinase AtPK1/AtPK6(ATPK1),Yeast
  • 货号：
    CSB-EP337226DOA
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Serine/threonine-protein kinase AtPK1/AtPK6(ATPK1),Yeast
  • 货号：
    CSB-EP337226DOA-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Serine/threonine-protein kinase AtPK1/AtPK6(ATPK1),Yeast
  • 货号：
    CSB-BP337226DOA
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Arabidopsis thaliana Serine/threonine-protein kinase AtPK1/AtPK6(ATPK1),Yeast
  • 货号：
    CSB-MP337226DOA
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ATPK1
  • Uniprot No.：
  • 别名：
    ATPK1; ATPK6; S6K1; At3g08730; F17O14.20Serine/threonine-protein kinase AtPK1/AtPK6; EC 2.7.11.1; Ribosomal-protein S6 kinase homolog 1
  • 种属：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-465
  • 氨基酸序列
    MVSSQRPVPN KIQKQQYLSI SPSNSVLKDD VELEFSDVFG PLPEEANDIA YDEPAVVYSR SHSLVGPCSL DSHSLKLTKL TLLETEDSID LVECLEGESL KENDDFSGND DSDNEKALEG DLVKVSGVVG IDDFEVMKVV GKGAFGKVYQ VRKKETSEIY AMKVMRKDHI MEKNHAEYMK AERDILTKID HPFIVQLKYS FQTKYRLYLV LDFINGGHLF FQLYHQGLFR EDLARVYTAE IVSAVSHLHE KGIMHRDLKP ENILMDTDGH VMLTDFGLAK EFEENTRSNS MCGTTEYMAP EIVRGKGHDK AADWWSVGIL LYEMLTGKPP FLGSKGKIQQ KIVKDKIKLP QFLSNEAHAI LKGLLQKEPE RRLGSGLSGA EEIKQHKWFK GINWKKLEAR EVMPSFKPEV SGRQCIANFD KCWTDMSVLD SPASSPSSDP KANPFTNFTY VRPPPSFLHQ STTTL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and required for maintenance of chromosome stability and ploidy levels through the RBR1-E2F pathway. Mediates the phosphorylation of MRFs (e.g. MRF1).
  • 基因功能参考文献：
    1. A 12-amino acid core element in S6 kinase 1 (AtS6K1) was identified as an essential interacting region with Raptor1 protein. PMID: 28285138
    2. identified a 44-amino acid region at the N-terminal end of ribosomal S6 kinase 1 (S6K1) specifically interacted with Raptor1, indicating that this region may contain a functional equivalent of TOS (TOR-Signaling) motif present in mammalian TOR substrates PMID: 26920057
    3. S6K1 interacts with retinoblastoma related protein (RBR)1 via its N-terminal RBR binding motif, promotes its nuclear localization and consequent RBR-dependent repression of cell cycle genes through transcription factor E2FB. PMID: 23531690
    4. s propose that TOR functions in polysomes to maintain the active S6K1 (and thus eIF3h) phosphorylation status that is critical for translation reinitiation. PMID: 23524850
    5. The s found that S6K1 associates with the Retinoblastoma-related 1 (RBR1)-E2FB complex and this is partly mediated by its N-terminal LVxCxE motif. PMID: 20683442
    6. Arabidopsis RAPTOR1 (a TOR regulatory protein) interacts with the HEAT repeats of TOR and that RAPTOR1 regulates the activity of S6 kinase (S6K) in response to osmotic stress [S6K1] PMID: 16377759

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  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Protein kinase superfamily, AGC Ser/Thr protein kinase family, S6 kinase subfamily
  • 组织特异性：
    Expressed in all tissues.
  • 数据库链接：

    KEGG: ath:AT3G08730

    STRING: 3702.AT3G08730.1

    UniGene: At.23700