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Recombinant Bovine Interferon tau-2 (IFNT2)

  • 中文名称：
    牛IFNT2重组蛋白
  • 货号：
    CSB-YP348737BO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    牛IFNT2重组蛋白
  • 货号：
    CSB-EP348737BO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    牛IFNT2重组蛋白
  • 货号：
    CSB-EP348737BO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    牛IFNT2重组蛋白
  • 货号：
    CSB-BP348737BO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    牛IFNT2重组蛋白
  • 货号：
    CSB-MP348737BO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    IFNT2
  • Uniprot No.：
  • 别名：
    IFNT2Interferon tau-2; IFN-tau-2; Antiluteolysin; Trophoblast antiluteolytic protein; Trophoblast protein 1; TP-1; Trophoblastin
  • 种属：
    Bos taurus (Bovine)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-172
  • 氨基酸序列
    CYLSEDHMLG ARENLRLLAR MNRLSPHPCL QDRKDFGLPQ EMVEGNQLQK DQAISVLHEM LQQCFNLFYT EHSSAAWNTT LLEQLCTGLQ QQLEDLDACL GQVMEEKDSD MGRMGPILTV KKYFQGIHVY LKEKEYSDCA WEIIRMEMMR ALSSSTTLQK RLRKMGGDLN SL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.
  • 亚细胞定位：
    Secreted. Note=Secreted into the uterine lumen.
  • 蛋白家族：
    Alpha/beta interferon family, IFN-alphaII subfamily
  • 组织特异性：
    Constitutively and exclusively expressed in the mononuclear cells of the extraembryonic trophectoderm.
  • 数据库链接：

    UniGene: Bt.328