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  4. Recombinant Chicken DNA repair protein RAD51 homolog 1 (RAD51A)

Recombinant Chicken DNA repair protein RAD51 homolog 1 (RAD51A)

  • 中文名称：
    鸡RAD51A重组蛋白
  • 货号：
    CSB-YP019263CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    鸡RAD51A重组蛋白
  • 货号：
    CSB-EP019263CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    鸡RAD51A重组蛋白
  • 货号：
    CSB-EP019263CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    鸡RAD51A重组蛋白
  • 货号：
    CSB-BP019263CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    鸡RAD51A重组蛋白
  • 货号：
    CSB-MP019263CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    RAD51A
  • Uniprot No.：
  • 别名：
    RAD51A; RAD51; DNA repair protein RAD51 homolog 1
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-339
  • 氨基酸序列
    MAMQVQFEAS TDTSAEEESF GPEPISRLEQ CGINANDVKK LEEAGYHTVE SVAHAPKKEL LNIKGISEAK ADKILAEAAK LVPMGFTTAT EFHQRRSEII QITTGSKELD KLLQGGIETG SITELFGEFR TGKTQLCHTL AVTCQLPIDR GGGEGKAMYI DTEGTFRPER LLAVAERYGL SGSDVLDNVA YARGFNTDHQ TQLLYQASAM MAESRYALLI VDSATALYRT DYSGRGELSA RQMHLARFLR MLLRLADEFG VAVVITNQVV AQVDGAAMFA ADPKKPIGGN IIAHASTTRL YLRKGRGETR ICKIYDSPCL PEAEAMFAIN ADGVGDAKE
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange.
  • 基因功能参考文献：
    1. Collectively, the FANCI-FANCD2 complex-mediated stabilization of the RAD51 nucleoprotein filament may function to prevent destructive DNA degradation by exonucleases during replication and at stalled replication forks. PMID: 27694619
    2. Rad51 is assembled by H2AX and XRCC3 in different pathways. PMID: 17123873
    3. suggest a model for the vertebrate cell cycle in which homologous DNA recombination during the G2 phase is separated from DNA replication in S phase and chromosome segregation in M PMID: 18794841
  • 亚细胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    RecA family, RAD51 subfamily
  • 组织特异性：
    Expressed at high levels in lymphoid and reproductive organs.
  • 数据库链接：

    KEGG: gga:396086

    STRING: 9031.ENSGALP00000032107

    UniGene: Gga.2303