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  4. Recombinant Chicken Protein sprouty homolog 2 (SPRY2)

Recombinant Chicken Protein sprouty homolog 2 (SPRY2)

  • 中文名称：
    鸡SPRY2重组蛋白
  • 货号：
    CSB-YP868696CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    鸡SPRY2重组蛋白
  • 货号：
    CSB-EP868696CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    鸡SPRY2重组蛋白
  • 货号：
    CSB-EP868696CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    鸡SPRY2重组蛋白
  • 货号：
    CSB-BP868696CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    鸡SPRY2重组蛋白
  • 货号：
    CSB-MP868696CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SPRY2
  • Uniprot No.：
  • 别名：
    SPRY2; Protein sprouty homolog 2; Spry-2
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-313
  • 氨基酸序列
    METRVQHGSG SQALLQARRD SGRPHGEPDL RDVLTQQVHI LSLDQIRAIR NTNEYTEGPT VAPRPGVKSA PRSASQPKSE RPHGLPEHRH FGRVQHTQTH ASPRAPLSRS ISTVSTGSRS STRTSTSSNS SEQRLLGSSS GPVADGIVRM QPKSELKSSE LKPLSKEDLG AHSYRCEDCG KCKCKECTYP RTLPSCWICD KQCLCSAQNV VDYGTCVCCV KGLFYHCSND DEDNCADNPC SCSQSHCCTR WSAMGVVSLF LPCLWCYLPA KGCLKLCQGC YDRVNRPGCR CKHSNTVCCK VPSVPPRNFE KPT
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts as an antagonist of FGF-induced retinal lens fiber differentiation. Inhibits TGFB-induced epithelial-to-mesenchymal transition in retinal lens epithelial cells. May play an important role in FGF-mediated patterning of the mid/hindbrain region by acting to modulate the signaling effects of FGF8.
  • 基因功能参考文献：
    1. Spry2 function during chick somite myogenesis PMID: 25783674
    2. 'Prolonged' activation of ERK by misexpression of Fgf8b and dominant-negative Sprouty2 (dnSprouty2) did not change the fate of the mesencephalic alar plate. PMID: 19896936
    3. Sprouty2 may regulate the Fgf8-Ras-ERK signaling pathway for the proper regionalization of the metencephalon and mesencephalon PMID: 15590739
    4. Sprouty2 plays a role in the outgrowth of facial prominences independent of canonical fibroblast growth factor signaling. PMID: 17576140
  • 亚细胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein.
  • 蛋白家族：
    Sprouty family
  • 组织特异性：
    Brain and interlimb region.
  • 数据库链接：

    KEGG: gga:395584

    STRING: 9031.ENSGALP00000027276

    UniGene: Gga.3374