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  4. Recombinant Chicken Telomeric repeat-binding factor 2-interacting protein 1 (TERF2IP)

Recombinant Chicken Telomeric repeat-binding factor 2-interacting protein 1 (TERF2IP)

  • 中文名称：
    鸡TERF2IP重组蛋白
  • 货号：
    CSB-YP749221CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    鸡TERF2IP重组蛋白
  • 货号：
    CSB-EP749221CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    鸡TERF2IP重组蛋白
  • 货号：
    CSB-EP749221CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    鸡TERF2IP重组蛋白
  • 货号：
    CSB-BP749221CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    鸡TERF2IP重组蛋白
  • 货号：
    CSB-MP749221CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    TERF2IP
  • Uniprot No.：
  • 别名：
    TERF2IP; RAP1; Telomeric repeat-binding factor 2-interacting protein 1; TERF2-interacting telomeric protein 1; TRF2-interacting telomeric protein 1; Repressor/activator protein 1 homolog; RAP1 homolog; cRAP1
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-329
  • 氨基酸序列
    MAAPPRKVFV WEDGTPMRFY IRPGMAKLRL APLLLAGGAG LCRVQEPGAV HLVQPGEPAP DGAVSTDYVV ACVESQRRLP LDLYRHSGPA PLAASPRGRL PFTEAEDAAL LRAVRERSGA PRVSGTALWK ELECTGLTRH SWQAMRDRYL RHLRPLHRES QQTEEAAAPM GIFEAANREF ESSESGSDTS DTPDELPLQN GEGTFPLEAA SGLQTGLDDC ALPAAQGENK QTNTFSDSSK AEEAAQIIQH FMEEFHTDLL TVTQALLKNS GEVEATSYYL HAGQRLDGYP VWSREDDLEL QKDDEDVRSK LIAKFGAENV ARRVAFRKS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
  • 基因功能参考文献：
    1. JunD and AP-1 antagonize the induction of DAPK1 to promote the survival of v-Src-transformed cells. PMID: 27795443
  • 亚细胞定位：
    Nucleus. Chromosome, telomere.
  • 蛋白家族：
    RAP1 family
  • 数据库链接：

    KEGG: gga:395122

    STRING: 9031.ENSGALP00000001323

    UniGene: Gga.32068