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  4. Recombinant Drosophila melanogaster Guanine nucleotide-binding protein subunit beta-like protein (Rack1)

Recombinant Drosophila melanogaster Guanine nucleotide-binding protein subunit beta-like protein (Rack1)

  • 中文名称：
    黑腹果蝇Rack1重组蛋白
  • 货号：
    CSB-YP515727DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇Rack1重组蛋白
  • 货号：
    CSB-EP515727DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇Rack1重组蛋白
  • 货号：
    CSB-EP515727DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇Rack1重组蛋白
  • 货号：
    CSB-BP515727DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇Rack1重组蛋白
  • 货号：
    CSB-MP515727DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Rack1
  • Uniprot No.：
  • 别名：
    Rack1; CG7111Guanine nucleotide-binding protein subunit beta-like protein; Receptor of activated protein kinase C homolog
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-318
  • 氨基酸序列
    MSETLQLRGT LIGHNGWVTQ IATNPKDPDT IISASRDKTL IVWKLTRDED TNYGYPQKRL YGHSHFISDV VLSSDGNYAL SGSWDQTLRL WDLAAGKTTR RFEGHTKDVL SVAFSADNRQ IVSGSRDKTI KLWNTLAECK FTIQEDGHTD WVSCVRFSPN HSNPIIVSCG WDRTVKVWNL ANCKLKNNHH GHNGYLNTVT VSPDGSLCTS GGKDSKALLW DLNDGKNLYT LEHNDIINAL CFSPNRYWLC VAYGPSIKIW DLACKKTVEE LRPEVVSPTS KADQPQCLSL AWSTDGQTLF AGYSDNTIRV WQVSVSAH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes.
  • 基因功能参考文献：
    1. A functional screen did not reveal any protein sharing the interesting properties of RACK1, which is required for IRES-dependent translation and not essential for cell viability. Intriguingly however, 10 of the RACK1 partners identified restrict replication of Cricket paralysis virus (CrPV), an IRES-containing virus. PMID: 28522639
    2. Using the model organism Drosophila melanogaster, studyidentify the ribosomal protein RACK1 as a cellular factor required for infection by internal ribosome entry site (IRES)-containing viruses. PMID: 25416947
    3. Data show that the genetic interaction between p38b MAPK and Rack1 controls muscle aggregate formation, locomotor function, and longevity. PMID: 24277934
    4. The fundamental role of Rack1 in autophagy and glycogen synthesis, is reported. PMID: 22562043
    5. RACK1 is essential at multiple steps of Drosophila development, particularly in oogenesis, where somatic RACK1 is required for proper germ-line function. PMID: 17584887

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  • 蛋白家族：
    WD repeat G protein beta family, Ribosomal protein RACK1 subfamily
  • 组织特异性：
    Highest expression in the mesodermal and endodermal lineages.
  • 数据库链接：

    KEGG: dme:Dmel_CG7111

    STRING: 7227.FBpp0303680

    UniGene: Dm.6830